Genetic expression of aryl hydrocarbon hydroxylase activity. Induction of monooxygenase activities and cytochrome P1-450 formation by 2,3,7,8-tetrachlorodibenzo-p-dioxin in mice genetically "nonresponsive" to other aromatic hydrocarbons

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Veröffentlicht in:	The Journal of biological chemistry 1974-09, Vol.249 (17), p.5599
Hauptverfasser:	Poland, A P, Glover, E, Robinson, J R, Nebert, D W
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Binding Sites Carbon Monoxide Cytochrome P-450 Enzyme System - biosynthesis Dioxins - pharmacology Electron Spin Resonance Spectroscopy Enzyme Induction - drug effects Female Genes Intestines - drug effects Intestines - enzymology Kidney - drug effects Kidney - enzymology Liver - drug effects Liver - enzymology Lung - drug effects Lung - enzymology Mice Mice, Inbred Strains Mixed Function Oxygenases - biosynthesis Organ Specificity Protein Binding Skin - drug effects Skin - enzymology Species Specificity Spectrophotometry Time Factors
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ISSN:	0021-9258