Aberrations of Cyclic Nucleotide Metabolism in the Hearts and Vessels of Hypertensive Rats

In the aortas and mesenteric arteries from spontaneous hypertensive rats and in the aortas from stress- and desoxycorticosterone-acetate-hypertensive rats, the intracellular cGMP: cAMP ratios were significantly elevated when compared to the ratios in the aortas of the respective controls. Decreases...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1974-12, Vol.71 (12), p.4930-4934
Hauptverfasser:	Amer, M. Samir, Gomoll, Allen W., Perhach, James L., Ferguson, Hugh C., McKinney, Gordon R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenylyl Cyclases - metabolism Animals Aorta Aorta, Thoracic - metabolism Biological Sciences: Cell Biology Cyclic AMP - metabolism Cyclic GMP - metabolism Cyclic nucleotides Desoxycorticosterone Enzymes Etiology Guanylate Cyclase - metabolism Heart Hypertension Hypertension - chemically induced Hypertension - metabolism Isoproterenol - pharmacology Mesenteric arteries Mesenteric Arteries - metabolism Metabolism Myocardium - metabolism Nucleotides, Cyclic - metabolism Phosphoric Diester Hydrolases - metabolism Rats Smooth muscle Stress, Physiological
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