Comparison of single-point insulin sensitivity estimator (SPISE) index and cognitive performance in vitamin B 12 -deficient young adults: An analytical cross-sectional study

Vitamin B is an essential micronutrient, aids in synthesis of neurotransmitters, and vital for cognitive function. In the current younger population with more of electronic gadgets and scientific world seems to slow down critical thinking and impairs the trick of comprehensive subjective learning. Vitamin B deficiency has been linked to insulin-resistant state and future cardiovascular risk. This study compared single-point insulin sensitivity estimator (SPISE) index, cognitive performance, and CVS risk in vitamin B -adequate and -deficient young adults. Study participants were 60 young female participants, 18 to 35 years with the inclusion criteria of BMI more than 22.9 and waist circumference >85 cm. Anthropometric variables were measured. Lipid profile analytes were analyzed in an integrated Beckman Coulter AU series autoanalyzer. Based on SPISE index categorized as insulin resistant Group A