RNA m 6 A methylation at the juxtaposition of apoptosis and RNA therapeutics

Targeting RNA m A marks in apoptosis-related transcripts holds promise for RNA therapeutics. However, pathway-specific RNA m A sites on pro- or antiapoptotic transcripts have not been fully unveiled, let alone characterized. This article summarizes the current knowledge and gaps in the cellular resp...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Trends in cell biology 2024-10, Vol.34 (10), p.801
Hauptverfasser:	Akgül, Bünyamin, Akçaöz-Alasar, Azime, Sağlam, Buket
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Humans Methylation RNA - genetics RNA - metabolism RNA Methylation
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

container_end_page
container_issue	10
container_start_page	801
container_title	Trends in cell biology
container_volume	34
creator	Akgül, Bünyamin Akçaöz-Alasar, Azime Sağlam, Buket
description	Targeting RNA m A marks in apoptosis-related transcripts holds promise for RNA therapeutics. However, pathway-specific RNA m A sites on pro- or antiapoptotic transcripts have not been fully unveiled, let alone characterized. This article summarizes the current knowledge and gaps in the cellular response modulated by apoptotic stimulus-specific RNA m A marks.
doi_str_mv	10.1016/j.tcb.2024.08.002
format	Article
fullrecord	<record><control><sourceid>pubmed</sourceid><recordid>TN_cdi_pubmed_primary_39218733</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>39218733</sourcerecordid><originalsourceid>FETCH-pubmed_primary_392187333</originalsourceid><addsrcrecordid>eNqFTUsKwjAUDIJo_RzAjbwLGF8SaetSRHEhLsR9STWlKf2EJgV7e6Po2s0M82MIWTCkDFm4Lqi7p5Qj31CMKSIfkIDF0XYlMI7HZGJtgYgRZ2JExmLLfSZEQM7Xyw4qCMGjcnlfSqebGqQDlysouqeTprH6YzYZeGGc1xZk_YD31tdaaVTn9N3OyDCTpVXzL0_J8ni47U8r06WVeiSm1ZVs--R3L_4WXuaOP9M</addsrcrecordid><sourcetype>Index Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>RNA m 6 A methylation at the juxtaposition of apoptosis and RNA therapeutics</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Akgül, Bünyamin ; Akçaöz-Alasar, Azime ; Sağlam, Buket</creator><creatorcontrib>Akgül, Bünyamin ; Akçaöz-Alasar, Azime ; Sağlam, Buket</creatorcontrib><description>Targeting RNA m A marks in apoptosis-related transcripts holds promise for RNA therapeutics. However, pathway-specific RNA m A sites on pro- or antiapoptotic transcripts have not been fully unveiled, let alone characterized. This article summarizes the current knowledge and gaps in the cellular response modulated by apoptotic stimulus-specific RNA m A marks.</description><identifier>EISSN: 1879-3088</identifier><identifier>DOI: 10.1016/j.tcb.2024.08.002</identifier><identifier>PMID: 39218733</identifier><language>eng</language><publisher>England</publisher><subject>Animals ; Apoptosis ; Humans ; Methylation ; RNA - genetics ; RNA - metabolism ; RNA Methylation</subject><ispartof>Trends in cell biology, 2024-10, Vol.34 (10), p.801</ispartof><rights>Copyright © 2024 Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39218733$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Akgül, Bünyamin</creatorcontrib><creatorcontrib>Akçaöz-Alasar, Azime</creatorcontrib><creatorcontrib>Sağlam, Buket</creatorcontrib><title>RNA m 6 A methylation at the juxtaposition of apoptosis and RNA therapeutics</title><title>Trends in cell biology</title><addtitle>Trends Cell Biol</addtitle><description>Targeting RNA m A marks in apoptosis-related transcripts holds promise for RNA therapeutics. However, pathway-specific RNA m A sites on pro- or antiapoptotic transcripts have not been fully unveiled, let alone characterized. This article summarizes the current knowledge and gaps in the cellular response modulated by apoptotic stimulus-specific RNA m A marks.</description><subject>Animals</subject><subject>Apoptosis</subject><subject>Humans</subject><subject>Methylation</subject><subject>RNA - genetics</subject><subject>RNA - metabolism</subject><subject>RNA Methylation</subject><issn>1879-3088</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFTUsKwjAUDIJo_RzAjbwLGF8SaetSRHEhLsR9STWlKf2EJgV7e6Po2s0M82MIWTCkDFm4Lqi7p5Qj31CMKSIfkIDF0XYlMI7HZGJtgYgRZ2JExmLLfSZEQM7Xyw4qCMGjcnlfSqebGqQDlysouqeTprH6YzYZeGGc1xZk_YD31tdaaVTn9N3OyDCTpVXzL0_J8ni47U8r06WVeiSm1ZVs--R3L_4WXuaOP9M</recordid><startdate>202410</startdate><enddate>202410</enddate><creator>Akgül, Bünyamin</creator><creator>Akçaöz-Alasar, Azime</creator><creator>Sağlam, Buket</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope></search><sort><creationdate>202410</creationdate><title>RNA m 6 A methylation at the juxtaposition of apoptosis and RNA therapeutics</title><author>Akgül, Bünyamin ; Akçaöz-Alasar, Azime ; Sağlam, Buket</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-pubmed_primary_392187333</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Animals</topic><topic>Apoptosis</topic><topic>Humans</topic><topic>Methylation</topic><topic>RNA - genetics</topic><topic>RNA - metabolism</topic><topic>RNA Methylation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Akgül, Bünyamin</creatorcontrib><creatorcontrib>Akçaöz-Alasar, Azime</creatorcontrib><creatorcontrib>Sağlam, Buket</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><jtitle>Trends in cell biology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Akgül, Bünyamin</au><au>Akçaöz-Alasar, Azime</au><au>Sağlam, Buket</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>RNA m 6 A methylation at the juxtaposition of apoptosis and RNA therapeutics</atitle><jtitle>Trends in cell biology</jtitle><addtitle>Trends Cell Biol</addtitle><date>2024-10</date><risdate>2024</risdate><volume>34</volume><issue>10</issue><spage>801</spage><pages>801-</pages><eissn>1879-3088</eissn><abstract>Targeting RNA m A marks in apoptosis-related transcripts holds promise for RNA therapeutics. However, pathway-specific RNA m A sites on pro- or antiapoptotic transcripts have not been fully unveiled, let alone characterized. This article summarizes the current knowledge and gaps in the cellular response modulated by apoptotic stimulus-specific RNA m A marks.</abstract><cop>England</cop><pmid>39218733</pmid><doi>10.1016/j.tcb.2024.08.002</doi></addata></record>
fulltext	fulltext
identifier	EISSN: 1879-3088
ispartof	Trends in cell biology, 2024-10, Vol.34 (10), p.801
issn	1879-3088
language	eng
recordid	cdi_pubmed_primary_39218733
source	MEDLINE; Elsevier ScienceDirect Journals
subjects	Animals Apoptosis Humans Methylation RNA - genetics RNA - metabolism RNA Methylation
title	RNA m 6 A methylation at the juxtaposition of apoptosis and RNA therapeutics
url	https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-27T22%3A19%3A48IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-pubmed&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=RNA%20m%206%20A%20methylation%20at%20the%20juxtaposition%20of%20apoptosis%20and%20RNA%20therapeutics&rft.jtitle=Trends%20in%20cell%20biology&rft.au=Akg%C3%BCl,%20B%C3%BCnyamin&rft.date=2024-10&rft.volume=34&rft.issue=10&rft.spage=801&rft.pages=801-&rft.eissn=1879-3088&rft_id=info:doi/10.1016/j.tcb.2024.08.002&rft_dat=%3Cpubmed%3E39218733%3C/pubmed%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/39218733&rfr_iscdi=true