RNA m 6 A methylation at the juxtaposition of apoptosis and RNA therapeutics

Targeting RNA m A marks in apoptosis-related transcripts holds promise for RNA therapeutics. However, pathway-specific RNA m A sites on pro- or antiapoptotic transcripts have not been fully unveiled, let alone characterized. This article summarizes the current knowledge and gaps in the cellular resp...

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Veröffentlicht in:Trends in cell biology 2024-10, Vol.34 (10), p.801
Hauptverfasser: Akgül, Bünyamin, Akçaöz-Alasar, Azime, Sağlam, Buket
Format: Artikel
Sprache:eng
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Zusammenfassung:Targeting RNA m A marks in apoptosis-related transcripts holds promise for RNA therapeutics. However, pathway-specific RNA m A sites on pro- or antiapoptotic transcripts have not been fully unveiled, let alone characterized. This article summarizes the current knowledge and gaps in the cellular response modulated by apoptotic stimulus-specific RNA m A marks.
ISSN:1879-3088
DOI:10.1016/j.tcb.2024.08.002