A critical review of the literature on acrolein toxicity
A detailed literature review of human and animal toxicity studies of acrolein is presented, and information gaps identified that call for further investigation. Specific recommendations are suggested for additional short-/long-term studies, including chemical disposition and cytogenetic investigatio...
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| Veröffentlicht in: | CRC Crit. Rev. Toxicol.; (United States) 1985, Vol.14 (4), p.309-380 |
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| container_title | CRC Crit. Rev. Toxicol.; (United States) |
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| creator | Beauchamp, Robert O. Andjelkovich, Dragana A. Kligerman, Andrew D. Morgan, Kevin T. Heck, Henry d'A. Feron, V. J. |
| description | A detailed literature review of human and animal toxicity studies of acrolein is presented, and information gaps identified that call for further investigation. Specific recommendations are suggested for additional short-/long-term studies, including chemical disposition and cytogenetic investigations. Two bibliographies are provided indicating the scope of the review: (1) literature actually cited and (2) literature examined but not included. |
| doi_str_mv | 10.3109/10408448509037461 |
| format | Article |
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Two bibliographies are provided indicating the scope of the review: (1) literature actually cited and (2) literature examined but not included.</description><identifier>ISSN: 1040-8444</identifier><identifier>ISSN: 0045-6446</identifier><identifier>EISSN: 1547-6898</identifier><identifier>DOI: 10.3109/10408448509037461</identifier><identifier>PMID: 3902372</identifier><language>eng</language><publisher>Cleveland, OH: Informa UK Ltd</publisher><subject>560306 - Chemicals Metabolism & Toxicology- Man- (-1987) ; ABSORPTION ; ACROLEIN ; Acrolein - adverse effects ; Acrolein - metabolism ; Acrolein - toxicity ; Air Pollutants, Occupational - toxicity ; AIR POLLUTION ; ALDEHYDES ; Aldehydes - toxicity ; Animals ; Biological and medical sciences ; Biotransformation ; BODY ; CARCINOGENS ; CARDIOVASCULAR SYSTEM ; Cardiovascular System - drug effects ; Chemical and Drug Induced Liver Injury - etiology ; Chemical and industrial products toxicology. Toxic occupational diseases ; CHROMOSOMAL ABERRATIONS ; Chromosome Aberrations - drug effects ; DIGESTIVE SYSTEM ; DOCUMENT TYPES ; Environmental Pollutants - toxicity ; Eye Diseases - chemically induced ; GLANDS ; Humans ; INTESTINAL ABSORPTION ; Kidney Diseases - chemically induced ; KIDNEYS ; LIVER ; LUNGS ; Medical sciences ; MUTATIONS ; ORGANIC COMPOUNDS ; ORGANS ; POLLUTION ; RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT ; RESPIRATORY SYSTEM ; Respiratory Tract Diseases - chemically induced ; REVIEWS ; TERATOGENS ; TOXICITY ; Toxicology ; UPTAKE ; Various organic compounds ; Water Pollutants, Chemical - toxicity ; WATER POLLUTION</subject><ispartof>CRC Crit. Rev. Toxicol.; (United States), 1985, Vol.14 (4), p.309-380</ispartof><rights>1985 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 1985</rights><rights>1986 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c523t-9ddbb535b91f5fc04fbdebc8c44f9b014a5eb5ddfb993b574b14f8e857dc673c3</citedby><cites>FETCH-LOGICAL-c523t-9ddbb535b91f5fc04fbdebc8c44f9b014a5eb5ddfb993b574b14f8e857dc673c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.tandfonline.com/doi/pdf/10.3109/10408448509037461$$EPDF$$P50$$Ginformaworld$$H</linktopdf><linktohtml>$$Uhttps://www.tandfonline.com/doi/full/10.3109/10408448509037461$$EHTML$$P50$$Ginformaworld$$H</linktohtml><link.rule.ids>314,776,780,881,4010,27900,27901,27902,59620,60409,61194,61229,61375,61410</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=8474268$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3902372$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://www.osti.gov/biblio/6252565$$D View this record in Osti.gov$$Hfree_for_read</backlink></links><search><creatorcontrib>Beauchamp, Robert O.</creatorcontrib><creatorcontrib>Andjelkovich, Dragana A.</creatorcontrib><creatorcontrib>Kligerman, Andrew D.</creatorcontrib><creatorcontrib>Morgan, Kevin T.</creatorcontrib><creatorcontrib>Heck, Henry d'A.</creatorcontrib><creatorcontrib>Feron, V. J.</creatorcontrib><creatorcontrib>Chemical Industry Institute of Toxicology Research Triangle Park, NC</creatorcontrib><title>A critical review of the literature on acrolein toxicity</title><title>CRC Crit. Rev. Toxicol.; (United States)</title><addtitle>Crit Rev Toxicol</addtitle><description>A detailed literature review of human and animal toxicity studies of acrolein is presented, and information gaps identified that call for further investigation. Specific recommendations are suggested for additional short-/long-term studies, including chemical disposition and cytogenetic investigations. Two bibliographies are provided indicating the scope of the review: (1) literature actually cited and (2) literature examined but not included.</description><subject>560306 - Chemicals Metabolism & Toxicology- Man- (-1987)</subject><subject>ABSORPTION</subject><subject>ACROLEIN</subject><subject>Acrolein - adverse effects</subject><subject>Acrolein - metabolism</subject><subject>Acrolein - toxicity</subject><subject>Air Pollutants, Occupational - toxicity</subject><subject>AIR POLLUTION</subject><subject>ALDEHYDES</subject><subject>Aldehydes - toxicity</subject><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Biotransformation</subject><subject>BODY</subject><subject>CARCINOGENS</subject><subject>CARDIOVASCULAR SYSTEM</subject><subject>Cardiovascular System - drug effects</subject><subject>Chemical and Drug Induced Liver Injury - etiology</subject><subject>Chemical and industrial products toxicology. Toxic occupational diseases</subject><subject>CHROMOSOMAL ABERRATIONS</subject><subject>Chromosome Aberrations - drug effects</subject><subject>DIGESTIVE SYSTEM</subject><subject>DOCUMENT TYPES</subject><subject>Environmental Pollutants - toxicity</subject><subject>Eye Diseases - chemically induced</subject><subject>GLANDS</subject><subject>Humans</subject><subject>INTESTINAL ABSORPTION</subject><subject>Kidney Diseases - chemically induced</subject><subject>KIDNEYS</subject><subject>LIVER</subject><subject>LUNGS</subject><subject>Medical sciences</subject><subject>MUTATIONS</subject><subject>ORGANIC COMPOUNDS</subject><subject>ORGANS</subject><subject>POLLUTION</subject><subject>RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT</subject><subject>RESPIRATORY SYSTEM</subject><subject>Respiratory Tract Diseases - chemically induced</subject><subject>REVIEWS</subject><subject>TERATOGENS</subject><subject>TOXICITY</subject><subject>Toxicology</subject><subject>UPTAKE</subject><subject>Various organic compounds</subject><subject>Water Pollutants, Chemical - toxicity</subject><subject>WATER POLLUTION</subject><issn>1040-8444</issn><issn>0045-6446</issn><issn>1547-6898</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1985</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE9LwzAYh4Moc04_gAehiNdq0iRtgl7G8B8MvOi5JGlCM7pmJJlz395I50CEnRL4Pb_kfR8ALhG8xQjyOwQJZIQwCjnEFSnRERgjSqq8ZJwdp3vK8wSQU3AWwgJCWBWMjsAIc1jgqhgDNs2Ut9Eq0WVef1q9yZzJYquzzkbtRVx7nbk-E8q7Tts-i-7LKhu35-DEiC7oi905AR9Pj--zl3z-9vw6m85zRQscc940UlJMJUeGGgWJkY2WiilCDJcQEUG1pE1jJOdY0opIRAzTjFaNKius8ARcD--6EG0d0tdatcr1vVaxLgta0JImCA1QmjIEr0298nYp_LZGsP4xVf8zlTpXQ2e1lkvd7Bs7NSm_2eUiJDvGi17ZsMcYqUhRsoQ9DJjtjfNLsXG-a-ootp3zvx18aIr7P_VWiy62SnhdL9za90ntgR2-ASH3lWY</recordid><startdate>1985</startdate><enddate>1985</enddate><creator>Beauchamp, Robert O.</creator><creator>Andjelkovich, Dragana A.</creator><creator>Kligerman, Andrew D.</creator><creator>Morgan, Kevin T.</creator><creator>Heck, Henry d'A.</creator><creator>Feron, V. J.</creator><general>Informa UK Ltd</general><general>Taylor & Francis</general><general>Chemical Rubber co</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>OTOTI</scope></search><sort><creationdate>1985</creationdate><title>A critical review of the literature on acrolein toxicity</title><author>Beauchamp, Robert O. ; Andjelkovich, Dragana A. ; Kligerman, Andrew D. ; Morgan, Kevin T. ; Heck, Henry d'A. ; Feron, V. J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c523t-9ddbb535b91f5fc04fbdebc8c44f9b014a5eb5ddfb993b574b14f8e857dc673c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1985</creationdate><topic>560306 - Chemicals Metabolism & Toxicology- Man- (-1987)</topic><topic>ABSORPTION</topic><topic>ACROLEIN</topic><topic>Acrolein - adverse effects</topic><topic>Acrolein - metabolism</topic><topic>Acrolein - toxicity</topic><topic>Air Pollutants, Occupational - toxicity</topic><topic>AIR POLLUTION</topic><topic>ALDEHYDES</topic><topic>Aldehydes - toxicity</topic><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Biotransformation</topic><topic>BODY</topic><topic>CARCINOGENS</topic><topic>CARDIOVASCULAR SYSTEM</topic><topic>Cardiovascular System - drug effects</topic><topic>Chemical and Drug Induced Liver Injury - etiology</topic><topic>Chemical and industrial products toxicology. Toxic occupational diseases</topic><topic>CHROMOSOMAL ABERRATIONS</topic><topic>Chromosome Aberrations - drug effects</topic><topic>DIGESTIVE SYSTEM</topic><topic>DOCUMENT TYPES</topic><topic>Environmental Pollutants - toxicity</topic><topic>Eye Diseases - chemically induced</topic><topic>GLANDS</topic><topic>Humans</topic><topic>INTESTINAL ABSORPTION</topic><topic>Kidney Diseases - chemically induced</topic><topic>KIDNEYS</topic><topic>LIVER</topic><topic>LUNGS</topic><topic>Medical sciences</topic><topic>MUTATIONS</topic><topic>ORGANIC COMPOUNDS</topic><topic>ORGANS</topic><topic>POLLUTION</topic><topic>RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT</topic><topic>RESPIRATORY SYSTEM</topic><topic>Respiratory Tract Diseases - chemically induced</topic><topic>REVIEWS</topic><topic>TERATOGENS</topic><topic>TOXICITY</topic><topic>Toxicology</topic><topic>UPTAKE</topic><topic>Various organic compounds</topic><topic>Water Pollutants, Chemical - toxicity</topic><topic>WATER POLLUTION</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Beauchamp, Robert O.</creatorcontrib><creatorcontrib>Andjelkovich, Dragana A.</creatorcontrib><creatorcontrib>Kligerman, Andrew D.</creatorcontrib><creatorcontrib>Morgan, Kevin T.</creatorcontrib><creatorcontrib>Heck, Henry d'A.</creatorcontrib><creatorcontrib>Feron, V. 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J.</au><aucorp>Chemical Industry Institute of Toxicology Research Triangle Park, NC</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A critical review of the literature on acrolein toxicity</atitle><jtitle>CRC Crit. Rev. Toxicol.; (United States)</jtitle><addtitle>Crit Rev Toxicol</addtitle><date>1985</date><risdate>1985</risdate><volume>14</volume><issue>4</issue><spage>309</spage><epage>380</epage><pages>309-380</pages><issn>1040-8444</issn><issn>0045-6446</issn><eissn>1547-6898</eissn><abstract>A detailed literature review of human and animal toxicity studies of acrolein is presented, and information gaps identified that call for further investigation. Specific recommendations are suggested for additional short-/long-term studies, including chemical disposition and cytogenetic investigations. 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| fulltext | fulltext |
| identifier | ISSN: 1040-8444 |
| ispartof | CRC Crit. Rev. Toxicol.; (United States), 1985, Vol.14 (4), p.309-380 |
| issn | 1040-8444 0045-6446 1547-6898 |
| language | eng |
| recordid | cdi_pubmed_primary_3902372 |
| source | Taylor & Francis; MEDLINE; Taylor & Francis Medical Library - CRKN |
| subjects | 560306 - Chemicals Metabolism & Toxicology- Man- (-1987) ABSORPTION ACROLEIN Acrolein - adverse effects Acrolein - metabolism Acrolein - toxicity Air Pollutants, Occupational - toxicity AIR POLLUTION ALDEHYDES Aldehydes - toxicity Animals Biological and medical sciences Biotransformation BODY CARCINOGENS CARDIOVASCULAR SYSTEM Cardiovascular System - drug effects Chemical and Drug Induced Liver Injury - etiology Chemical and industrial products toxicology. Toxic occupational diseases CHROMOSOMAL ABERRATIONS Chromosome Aberrations - drug effects DIGESTIVE SYSTEM DOCUMENT TYPES Environmental Pollutants - toxicity Eye Diseases - chemically induced GLANDS Humans INTESTINAL ABSORPTION Kidney Diseases - chemically induced KIDNEYS LIVER LUNGS Medical sciences MUTATIONS ORGANIC COMPOUNDS ORGANS POLLUTION RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT RESPIRATORY SYSTEM Respiratory Tract Diseases - chemically induced REVIEWS TERATOGENS TOXICITY Toxicology UPTAKE Various organic compounds Water Pollutants, Chemical - toxicity WATER POLLUTION |
| title | A critical review of the literature on acrolein toxicity |
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