A critical review of the literature on acrolein toxicity

A detailed literature review of human and animal toxicity studies of acrolein is presented, and information gaps identified that call for further investigation. Specific recommendations are suggested for additional short-/long-term studies, including chemical disposition and cytogenetic investigatio...

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Veröffentlicht in:	CRC Crit. Rev. Toxicol.; (United States) 1985, Vol.14 (4), p.309-380
Hauptverfasser:	Beauchamp, Robert O., Andjelkovich, Dragana A., Kligerman, Andrew D., Morgan, Kevin T., Heck, Henry d'A., Feron, V. J.
Format:	Artikel
Sprache:	eng
Schlagworte:	560306 - Chemicals Metabolism & Toxicology- Man- (-1987) ABSORPTION ACROLEIN Acrolein - adverse effects Acrolein - metabolism Acrolein - toxicity Air Pollutants, Occupational - toxicity AIR POLLUTION ALDEHYDES Aldehydes - toxicity Animals Biological and medical sciences Biotransformation BODY CARCINOGENS CARDIOVASCULAR SYSTEM Cardiovascular System - drug effects Chemical and Drug Induced Liver Injury - etiology Chemical and industrial products toxicology. Toxic occupational diseases CHROMOSOMAL ABERRATIONS Chromosome Aberrations - drug effects DIGESTIVE SYSTEM DOCUMENT TYPES Environmental Pollutants - toxicity Eye Diseases - chemically induced GLANDS Humans INTESTINAL ABSORPTION Kidney Diseases - chemically induced KIDNEYS LIVER LUNGS Medical sciences MUTATIONS ORGANIC COMPOUNDS ORGANS POLLUTION RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT RESPIRATORY SYSTEM Respiratory Tract Diseases - chemically induced REVIEWS TERATOGENS TOXICITY Toxicology UPTAKE Various organic compounds Water Pollutants, Chemical - toxicity WATER POLLUTION
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Beschreibung
Zusammenfassung:	A detailed literature review of human and animal toxicity studies of acrolein is presented, and information gaps identified that call for further investigation. Specific recommendations are suggested for additional short-/long-term studies, including chemical disposition and cytogenetic investigations. Two bibliographies are provided indicating the scope of the review: (1) literature actually cited and (2) literature examined but not included.
ISSN:	1040-8444 0045-6446 1547-6898
DOI:	10.3109/10408448509037461