Flake-like structure of SrTiO 3 nanoparticles dispersed on graphene oxide: A selective and sensitive electrochemical sensor for determination of chloramphenicol in milk and honey samples

The use of Chloramphenicol (CAP), a potent antibiotic with broad-spectrum capabilities in food-producing animals has been restricted by the European Union and several other countries due to its severe side effects. Thus, CAP must be detected quickly and sensitively. In this investigation, the prepar...

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Veröffentlicht in:Food chemistry 2024-06, Vol.444, p.138637
Hauptverfasser: Sakaleshpur Kumar, Gagankumar, Ballur Prasanna, Sanjay, Lokesh Marenahalli, Bhuvan, Shadakshari, Sandeep, Arehalli Shivamurthy, Santhosh, Rajabathar, Jothi Ramalingam, Chimatahalli Shanthakumar, Karthik, Han, Young-Kyu
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Sprache:eng
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Zusammenfassung:The use of Chloramphenicol (CAP), a potent antibiotic with broad-spectrum capabilities in food-producing animals has been restricted by the European Union and several other countries due to its severe side effects. Thus, CAP must be detected quickly and sensitively. In this investigation, the preparation of SrTiO nanoparticles was carried out utilizing a hydrothermal technique. The as-synthesized strontium titanate was decorated on the graphene oxide (SrTiO /GO) using an ultrasonication method. An electrochemical sensor was developed by employing a modified electrode consisting of SrTiO /GO, which can accurately detect CAP in food samples. The synergistic effect of SrTiO and GO could improve the peak current response. Remarkably, the SrTiO /GO-modified glassy carbon electrode has a LOD and sensitivity of 6.08 µM nM and 2.771 µA·μM ·cm , respectively. This modified electrode was evaluated in food samples and had an outstanding reaction with a high percentage of recovery, which makes it a potential electrocatalyst for CAP detection.
ISSN:1873-7072