A comprehensive review and comparison of L-tryptophan biosynthesis in Saccharomyces cerevisia e and Escherichia coli
L-tryptophan and its derivatives are widely used in the chemical, pharmaceutical, food, and feed industries. Microbial fermentation is the most commonly used method to produce L-tryptophan, which calls for an effective cell factory. The mechanism of L-tryptophan biosynthesis in , the widely used pro...
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Veröffentlicht in: | Frontiers in bioengineering and biotechnology 2023, Vol.11, p.1261832 |
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creator | Ren, Xinru Wei, Yue Zhao, Honglu Shao, Juanjuan Zeng, Fanli Wang, Zhen Li, Li |
description | L-tryptophan and its derivatives are widely used in the chemical, pharmaceutical, food, and feed industries. Microbial fermentation is the most commonly used method to produce L-tryptophan, which calls for an effective cell factory. The mechanism of L-tryptophan biosynthesis in
, the widely used producer of L-tryptophan, is well understood.
also plays a significant role in the industrial production of biochemicals. Because of its robustness and safety,
is favored for producing pharmaceuticals and food-grade biochemicals. However, the biosynthesis of L-tryptophan in
has been rarely summarized. The synthetic pathways and engineering strategies of L-tryptophan in
and
have been reviewed and compared in this review. Furthermore, the information presented in this review pertains to the existing understanding of how L-tryptophan affects
stress fitness, which could aid in developing a novel plan to produce more resilient industrial yeast and
cell factories. |
format | Article |
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, the widely used producer of L-tryptophan, is well understood.
also plays a significant role in the industrial production of biochemicals. Because of its robustness and safety,
is favored for producing pharmaceuticals and food-grade biochemicals. However, the biosynthesis of L-tryptophan in
has been rarely summarized. The synthetic pathways and engineering strategies of L-tryptophan in
and
have been reviewed and compared in this review. Furthermore, the information presented in this review pertains to the existing understanding of how L-tryptophan affects
stress fitness, which could aid in developing a novel plan to produce more resilient industrial yeast and
cell factories.</description><identifier>ISSN: 2296-4185</identifier><identifier>EISSN: 2296-4185</identifier><identifier>PMID: 38116200</identifier><language>eng</language><publisher>Switzerland</publisher><ispartof>Frontiers in bioengineering and biotechnology, 2023, Vol.11, p.1261832</ispartof><rights>Copyright © 2023 Ren, Wei, Zhao, Shao, Zeng, Wang and Li.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,4024</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38116200$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ren, Xinru</creatorcontrib><creatorcontrib>Wei, Yue</creatorcontrib><creatorcontrib>Zhao, Honglu</creatorcontrib><creatorcontrib>Shao, Juanjuan</creatorcontrib><creatorcontrib>Zeng, Fanli</creatorcontrib><creatorcontrib>Wang, Zhen</creatorcontrib><creatorcontrib>Li, Li</creatorcontrib><title>A comprehensive review and comparison of L-tryptophan biosynthesis in Saccharomyces cerevisia e and Escherichia coli</title><title>Frontiers in bioengineering and biotechnology</title><addtitle>Front Bioeng Biotechnol</addtitle><description>L-tryptophan and its derivatives are widely used in the chemical, pharmaceutical, food, and feed industries. Microbial fermentation is the most commonly used method to produce L-tryptophan, which calls for an effective cell factory. The mechanism of L-tryptophan biosynthesis in
, the widely used producer of L-tryptophan, is well understood.
also plays a significant role in the industrial production of biochemicals. Because of its robustness and safety,
is favored for producing pharmaceuticals and food-grade biochemicals. However, the biosynthesis of L-tryptophan in
has been rarely summarized. The synthetic pathways and engineering strategies of L-tryptophan in
and
have been reviewed and compared in this review. Furthermore, the information presented in this review pertains to the existing understanding of how L-tryptophan affects
stress fitness, which could aid in developing a novel plan to produce more resilient industrial yeast and
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, the widely used producer of L-tryptophan, is well understood.
also plays a significant role in the industrial production of biochemicals. Because of its robustness and safety,
is favored for producing pharmaceuticals and food-grade biochemicals. However, the biosynthesis of L-tryptophan in
has been rarely summarized. The synthetic pathways and engineering strategies of L-tryptophan in
and
have been reviewed and compared in this review. Furthermore, the information presented in this review pertains to the existing understanding of how L-tryptophan affects
stress fitness, which could aid in developing a novel plan to produce more resilient industrial yeast and
cell factories.</abstract><cop>Switzerland</cop><pmid>38116200</pmid></addata></record> |
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title | A comprehensive review and comparison of L-tryptophan biosynthesis in Saccharomyces cerevisia e and Escherichia coli |
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