A fluorescence immunoassay based on GSH destroying MnO 2 @QDs for the simultaneous ultrasensitive detection of four mycotoxins in cereals

A novel fluorescence immunoassay based on MnO nanoflowers loading multicolor quantum dots and glutathione destroying MnO nanoflowers to release quantum dots combined with magnetic separation is developed for rapid, ultra-sensitive, and simultaneous quantitative detection of ochratoxin A, aflatoxin B...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Food chemistry 2023-09, Vol.420, p.136099
Hauptverfasser: Jin, Zixin, Sheng, Wei, Liu, Junli, Liu, Chenchen, Ma, Yueru, Wang, Shuo, Zhang, Wanli, Huang, Na
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page 136099
container_title Food chemistry
container_volume 420
creator Jin, Zixin
Sheng, Wei
Liu, Junli
Liu, Chenchen
Ma, Yueru
Wang, Shuo
Zhang, Wanli
Huang, Na
description A novel fluorescence immunoassay based on MnO nanoflowers loading multicolor quantum dots and glutathione destroying MnO nanoflowers to release quantum dots combined with magnetic separation is developed for rapid, ultra-sensitive, and simultaneous quantitative detection of ochratoxin A, aflatoxin B , fumonisin B , and zearalenone in cereal samples. The test linear range of assay is from 0.001 to 200 μg L . The limit of detection for ochratoxin A, aflatoxin B , fumonisin B , and zearalenone is 0.0001 μg L , 0.0001 μg L , 0.0003 μg L , and 0.0001 μg L , respectively. The simultaneous detection of four mycotoxins can be achieve within 30 min. The test results of four mycotoxins in the incurred corn, rice, and oat samples have been confirmed by ultra-performance liquid chromatography tandem mass spectrometry, the differences between results are considered no significantly different (p > 0.05). This multiplexed test scheme has provided a potential analysis strategy for multiple food risk factors.
doi_str_mv 10.1016/j.foodchem.2023.136099
format Article
fullrecord <record><control><sourceid>pubmed</sourceid><recordid>TN_cdi_pubmed_primary_37037114</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>37037114</sourcerecordid><originalsourceid>FETCH-pubmed_primary_370371143</originalsourceid><addsrcrecordid>eNqFjktOAzEQRC0kRMLnClFfIIM_KJPsQPyyQQjBPnI8PcTR2B25bcQcgVvjBVmzerWoVyohZko2SqrF9b7piTq3w9BoqU2jzEKuVidiqpatmbey1RNxzryXUmqplmdiYlppWqVupuLnDvqhUEJ2GB2CD6FEssx2hK1l7IAiPL-voUPOiUYfP-ElvoKG27cHhp4S5B0C-1CGbCNSYagpVTWyz_4Lq5nRZV93qK9CSRBGR5m-fWTwERwmtANfitO-Aq_-eCFmT48f9-v5oWwDdptD8sGmcXP8bv4t_AJnW1l6</addsrcrecordid><sourcetype>Index Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>A fluorescence immunoassay based on GSH destroying MnO 2 @QDs for the simultaneous ultrasensitive detection of four mycotoxins in cereals</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Jin, Zixin ; Sheng, Wei ; Liu, Junli ; Liu, Chenchen ; Ma, Yueru ; Wang, Shuo ; Zhang, Wanli ; Huang, Na</creator><creatorcontrib>Jin, Zixin ; Sheng, Wei ; Liu, Junli ; Liu, Chenchen ; Ma, Yueru ; Wang, Shuo ; Zhang, Wanli ; Huang, Na</creatorcontrib><description>A novel fluorescence immunoassay based on MnO nanoflowers loading multicolor quantum dots and glutathione destroying MnO nanoflowers to release quantum dots combined with magnetic separation is developed for rapid, ultra-sensitive, and simultaneous quantitative detection of ochratoxin A, aflatoxin B , fumonisin B , and zearalenone in cereal samples. The test linear range of assay is from 0.001 to 200 μg L . The limit of detection for ochratoxin A, aflatoxin B , fumonisin B , and zearalenone is 0.0001 μg L , 0.0001 μg L , 0.0003 μg L , and 0.0001 μg L , respectively. The simultaneous detection of four mycotoxins can be achieve within 30 min. The test results of four mycotoxins in the incurred corn, rice, and oat samples have been confirmed by ultra-performance liquid chromatography tandem mass spectrometry, the differences between results are considered no significantly different (p &gt; 0.05). This multiplexed test scheme has provided a potential analysis strategy for multiple food risk factors.</description><identifier>EISSN: 1873-7072</identifier><identifier>DOI: 10.1016/j.foodchem.2023.136099</identifier><identifier>PMID: 37037114</identifier><language>eng</language><publisher>England</publisher><subject>Aflatoxin B1 - analysis ; Edible Grain - chemistry ; Food Contamination - analysis ; Immunoassay - methods ; Limit of Detection ; Manganese Compounds ; Mycotoxins - analysis ; Oxides ; Zearalenone - analysis</subject><ispartof>Food chemistry, 2023-09, Vol.420, p.136099</ispartof><rights>Copyright © 2023 Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37037114$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jin, Zixin</creatorcontrib><creatorcontrib>Sheng, Wei</creatorcontrib><creatorcontrib>Liu, Junli</creatorcontrib><creatorcontrib>Liu, Chenchen</creatorcontrib><creatorcontrib>Ma, Yueru</creatorcontrib><creatorcontrib>Wang, Shuo</creatorcontrib><creatorcontrib>Zhang, Wanli</creatorcontrib><creatorcontrib>Huang, Na</creatorcontrib><title>A fluorescence immunoassay based on GSH destroying MnO 2 @QDs for the simultaneous ultrasensitive detection of four mycotoxins in cereals</title><title>Food chemistry</title><addtitle>Food Chem</addtitle><description>A novel fluorescence immunoassay based on MnO nanoflowers loading multicolor quantum dots and glutathione destroying MnO nanoflowers to release quantum dots combined with magnetic separation is developed for rapid, ultra-sensitive, and simultaneous quantitative detection of ochratoxin A, aflatoxin B , fumonisin B , and zearalenone in cereal samples. The test linear range of assay is from 0.001 to 200 μg L . The limit of detection for ochratoxin A, aflatoxin B , fumonisin B , and zearalenone is 0.0001 μg L , 0.0001 μg L , 0.0003 μg L , and 0.0001 μg L , respectively. The simultaneous detection of four mycotoxins can be achieve within 30 min. The test results of four mycotoxins in the incurred corn, rice, and oat samples have been confirmed by ultra-performance liquid chromatography tandem mass spectrometry, the differences between results are considered no significantly different (p &gt; 0.05). This multiplexed test scheme has provided a potential analysis strategy for multiple food risk factors.</description><subject>Aflatoxin B1 - analysis</subject><subject>Edible Grain - chemistry</subject><subject>Food Contamination - analysis</subject><subject>Immunoassay - methods</subject><subject>Limit of Detection</subject><subject>Manganese Compounds</subject><subject>Mycotoxins - analysis</subject><subject>Oxides</subject><subject>Zearalenone - analysis</subject><issn>1873-7072</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFjktOAzEQRC0kRMLnClFfIIM_KJPsQPyyQQjBPnI8PcTR2B25bcQcgVvjBVmzerWoVyohZko2SqrF9b7piTq3w9BoqU2jzEKuVidiqpatmbey1RNxzryXUmqplmdiYlppWqVupuLnDvqhUEJ2GB2CD6FEssx2hK1l7IAiPL-voUPOiUYfP-ElvoKG27cHhp4S5B0C-1CGbCNSYagpVTWyz_4Lq5nRZV93qK9CSRBGR5m-fWTwERwmtANfitO-Aq_-eCFmT48f9-v5oWwDdptD8sGmcXP8bv4t_AJnW1l6</recordid><startdate>20230915</startdate><enddate>20230915</enddate><creator>Jin, Zixin</creator><creator>Sheng, Wei</creator><creator>Liu, Junli</creator><creator>Liu, Chenchen</creator><creator>Ma, Yueru</creator><creator>Wang, Shuo</creator><creator>Zhang, Wanli</creator><creator>Huang, Na</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope></search><sort><creationdate>20230915</creationdate><title>A fluorescence immunoassay based on GSH destroying MnO 2 @QDs for the simultaneous ultrasensitive detection of four mycotoxins in cereals</title><author>Jin, Zixin ; Sheng, Wei ; Liu, Junli ; Liu, Chenchen ; Ma, Yueru ; Wang, Shuo ; Zhang, Wanli ; Huang, Na</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-pubmed_primary_370371143</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Aflatoxin B1 - analysis</topic><topic>Edible Grain - chemistry</topic><topic>Food Contamination - analysis</topic><topic>Immunoassay - methods</topic><topic>Limit of Detection</topic><topic>Manganese Compounds</topic><topic>Mycotoxins - analysis</topic><topic>Oxides</topic><topic>Zearalenone - analysis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jin, Zixin</creatorcontrib><creatorcontrib>Sheng, Wei</creatorcontrib><creatorcontrib>Liu, Junli</creatorcontrib><creatorcontrib>Liu, Chenchen</creatorcontrib><creatorcontrib>Ma, Yueru</creatorcontrib><creatorcontrib>Wang, Shuo</creatorcontrib><creatorcontrib>Zhang, Wanli</creatorcontrib><creatorcontrib>Huang, Na</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><jtitle>Food chemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jin, Zixin</au><au>Sheng, Wei</au><au>Liu, Junli</au><au>Liu, Chenchen</au><au>Ma, Yueru</au><au>Wang, Shuo</au><au>Zhang, Wanli</au><au>Huang, Na</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A fluorescence immunoassay based on GSH destroying MnO 2 @QDs for the simultaneous ultrasensitive detection of four mycotoxins in cereals</atitle><jtitle>Food chemistry</jtitle><addtitle>Food Chem</addtitle><date>2023-09-15</date><risdate>2023</risdate><volume>420</volume><spage>136099</spage><pages>136099-</pages><eissn>1873-7072</eissn><abstract>A novel fluorescence immunoassay based on MnO nanoflowers loading multicolor quantum dots and glutathione destroying MnO nanoflowers to release quantum dots combined with magnetic separation is developed for rapid, ultra-sensitive, and simultaneous quantitative detection of ochratoxin A, aflatoxin B , fumonisin B , and zearalenone in cereal samples. The test linear range of assay is from 0.001 to 200 μg L . The limit of detection for ochratoxin A, aflatoxin B , fumonisin B , and zearalenone is 0.0001 μg L , 0.0001 μg L , 0.0003 μg L , and 0.0001 μg L , respectively. The simultaneous detection of four mycotoxins can be achieve within 30 min. The test results of four mycotoxins in the incurred corn, rice, and oat samples have been confirmed by ultra-performance liquid chromatography tandem mass spectrometry, the differences between results are considered no significantly different (p &gt; 0.05). This multiplexed test scheme has provided a potential analysis strategy for multiple food risk factors.</abstract><cop>England</cop><pmid>37037114</pmid><doi>10.1016/j.foodchem.2023.136099</doi></addata></record>
fulltext fulltext
identifier EISSN: 1873-7072
ispartof Food chemistry, 2023-09, Vol.420, p.136099
issn 1873-7072
language eng
recordid cdi_pubmed_primary_37037114
source MEDLINE; Elsevier ScienceDirect Journals
subjects Aflatoxin B1 - analysis
Edible Grain - chemistry
Food Contamination - analysis
Immunoassay - methods
Limit of Detection
Manganese Compounds
Mycotoxins - analysis
Oxides
Zearalenone - analysis
title A fluorescence immunoassay based on GSH destroying MnO 2 @QDs for the simultaneous ultrasensitive detection of four mycotoxins in cereals
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-30T23%3A34%3A41IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-pubmed&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20fluorescence%20immunoassay%20based%20on%20GSH%20destroying%20MnO%202%20@QDs%20for%20the%20simultaneous%20ultrasensitive%20detection%20of%20four%20mycotoxins%20in%20cereals&rft.jtitle=Food%20chemistry&rft.au=Jin,%20Zixin&rft.date=2023-09-15&rft.volume=420&rft.spage=136099&rft.pages=136099-&rft.eissn=1873-7072&rft_id=info:doi/10.1016/j.foodchem.2023.136099&rft_dat=%3Cpubmed%3E37037114%3C/pubmed%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/37037114&rfr_iscdi=true