A fluorescence immunoassay based on GSH destroying MnO 2 @QDs for the simultaneous ultrasensitive detection of four mycotoxins in cereals
A novel fluorescence immunoassay based on MnO nanoflowers loading multicolor quantum dots and glutathione destroying MnO nanoflowers to release quantum dots combined with magnetic separation is developed for rapid, ultra-sensitive, and simultaneous quantitative detection of ochratoxin A, aflatoxin B...
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Veröffentlicht in: | Food chemistry 2023-09, Vol.420, p.136099 |
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creator | Jin, Zixin Sheng, Wei Liu, Junli Liu, Chenchen Ma, Yueru Wang, Shuo Zhang, Wanli Huang, Na |
description | A novel fluorescence immunoassay based on MnO
nanoflowers loading multicolor quantum dots and glutathione destroying MnO
nanoflowers to release quantum dots combined with magnetic separation is developed for rapid, ultra-sensitive, and simultaneous quantitative detection of ochratoxin A, aflatoxin B
, fumonisin B
, and zearalenone in cereal samples. The test linear range of assay is from 0.001 to 200 μg L
. The limit of detection for ochratoxin A, aflatoxin B
, fumonisin B
, and zearalenone is 0.0001 μg L
, 0.0001 μg L
, 0.0003 μg L
, and 0.0001 μg L
, respectively. The simultaneous detection of four mycotoxins can be achieve within 30 min. The test results of four mycotoxins in the incurred corn, rice, and oat samples have been confirmed by ultra-performance liquid chromatography tandem mass spectrometry, the differences between results are considered no significantly different (p > 0.05). This multiplexed test scheme has provided a potential analysis strategy for multiple food risk factors. |
doi_str_mv | 10.1016/j.foodchem.2023.136099 |
format | Article |
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nanoflowers loading multicolor quantum dots and glutathione destroying MnO
nanoflowers to release quantum dots combined with magnetic separation is developed for rapid, ultra-sensitive, and simultaneous quantitative detection of ochratoxin A, aflatoxin B
, fumonisin B
, and zearalenone in cereal samples. The test linear range of assay is from 0.001 to 200 μg L
. The limit of detection for ochratoxin A, aflatoxin B
, fumonisin B
, and zearalenone is 0.0001 μg L
, 0.0001 μg L
, 0.0003 μg L
, and 0.0001 μg L
, respectively. The simultaneous detection of four mycotoxins can be achieve within 30 min. The test results of four mycotoxins in the incurred corn, rice, and oat samples have been confirmed by ultra-performance liquid chromatography tandem mass spectrometry, the differences between results are considered no significantly different (p > 0.05). This multiplexed test scheme has provided a potential analysis strategy for multiple food risk factors.</description><identifier>EISSN: 1873-7072</identifier><identifier>DOI: 10.1016/j.foodchem.2023.136099</identifier><identifier>PMID: 37037114</identifier><language>eng</language><publisher>England</publisher><subject>Aflatoxin B1 - analysis ; Edible Grain - chemistry ; Food Contamination - analysis ; Immunoassay - methods ; Limit of Detection ; Manganese Compounds ; Mycotoxins - analysis ; Oxides ; Zearalenone - analysis</subject><ispartof>Food chemistry, 2023-09, Vol.420, p.136099</ispartof><rights>Copyright © 2023 Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37037114$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jin, Zixin</creatorcontrib><creatorcontrib>Sheng, Wei</creatorcontrib><creatorcontrib>Liu, Junli</creatorcontrib><creatorcontrib>Liu, Chenchen</creatorcontrib><creatorcontrib>Ma, Yueru</creatorcontrib><creatorcontrib>Wang, Shuo</creatorcontrib><creatorcontrib>Zhang, Wanli</creatorcontrib><creatorcontrib>Huang, Na</creatorcontrib><title>A fluorescence immunoassay based on GSH destroying MnO 2 @QDs for the simultaneous ultrasensitive detection of four mycotoxins in cereals</title><title>Food chemistry</title><addtitle>Food Chem</addtitle><description>A novel fluorescence immunoassay based on MnO
nanoflowers loading multicolor quantum dots and glutathione destroying MnO
nanoflowers to release quantum dots combined with magnetic separation is developed for rapid, ultra-sensitive, and simultaneous quantitative detection of ochratoxin A, aflatoxin B
, fumonisin B
, and zearalenone in cereal samples. The test linear range of assay is from 0.001 to 200 μg L
. The limit of detection for ochratoxin A, aflatoxin B
, fumonisin B
, and zearalenone is 0.0001 μg L
, 0.0001 μg L
, 0.0003 μg L
, and 0.0001 μg L
, respectively. The simultaneous detection of four mycotoxins can be achieve within 30 min. The test results of four mycotoxins in the incurred corn, rice, and oat samples have been confirmed by ultra-performance liquid chromatography tandem mass spectrometry, the differences between results are considered no significantly different (p > 0.05). This multiplexed test scheme has provided a potential analysis strategy for multiple food risk factors.</description><subject>Aflatoxin B1 - analysis</subject><subject>Edible Grain - chemistry</subject><subject>Food Contamination - analysis</subject><subject>Immunoassay - methods</subject><subject>Limit of Detection</subject><subject>Manganese Compounds</subject><subject>Mycotoxins - analysis</subject><subject>Oxides</subject><subject>Zearalenone - analysis</subject><issn>1873-7072</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFjktOAzEQRC0kRMLnClFfIIM_KJPsQPyyQQjBPnI8PcTR2B25bcQcgVvjBVmzerWoVyohZko2SqrF9b7piTq3w9BoqU2jzEKuVidiqpatmbey1RNxzryXUmqplmdiYlppWqVupuLnDvqhUEJ2GB2CD6FEssx2hK1l7IAiPL-voUPOiUYfP-ElvoKG27cHhp4S5B0C-1CGbCNSYagpVTWyz_4Lq5nRZV93qK9CSRBGR5m-fWTwERwmtANfitO-Aq_-eCFmT48f9-v5oWwDdptD8sGmcXP8bv4t_AJnW1l6</recordid><startdate>20230915</startdate><enddate>20230915</enddate><creator>Jin, Zixin</creator><creator>Sheng, Wei</creator><creator>Liu, Junli</creator><creator>Liu, Chenchen</creator><creator>Ma, Yueru</creator><creator>Wang, Shuo</creator><creator>Zhang, Wanli</creator><creator>Huang, Na</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope></search><sort><creationdate>20230915</creationdate><title>A fluorescence immunoassay based on GSH destroying MnO 2 @QDs for the simultaneous ultrasensitive detection of four mycotoxins in cereals</title><author>Jin, Zixin ; Sheng, Wei ; Liu, Junli ; Liu, Chenchen ; Ma, Yueru ; Wang, Shuo ; Zhang, Wanli ; Huang, Na</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-pubmed_primary_370371143</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Aflatoxin B1 - analysis</topic><topic>Edible Grain - chemistry</topic><topic>Food Contamination - analysis</topic><topic>Immunoassay - methods</topic><topic>Limit of Detection</topic><topic>Manganese Compounds</topic><topic>Mycotoxins - analysis</topic><topic>Oxides</topic><topic>Zearalenone - analysis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jin, Zixin</creatorcontrib><creatorcontrib>Sheng, Wei</creatorcontrib><creatorcontrib>Liu, Junli</creatorcontrib><creatorcontrib>Liu, Chenchen</creatorcontrib><creatorcontrib>Ma, Yueru</creatorcontrib><creatorcontrib>Wang, Shuo</creatorcontrib><creatorcontrib>Zhang, Wanli</creatorcontrib><creatorcontrib>Huang, Na</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><jtitle>Food chemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jin, Zixin</au><au>Sheng, Wei</au><au>Liu, Junli</au><au>Liu, Chenchen</au><au>Ma, Yueru</au><au>Wang, Shuo</au><au>Zhang, Wanli</au><au>Huang, Na</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A fluorescence immunoassay based on GSH destroying MnO 2 @QDs for the simultaneous ultrasensitive detection of four mycotoxins in cereals</atitle><jtitle>Food chemistry</jtitle><addtitle>Food Chem</addtitle><date>2023-09-15</date><risdate>2023</risdate><volume>420</volume><spage>136099</spage><pages>136099-</pages><eissn>1873-7072</eissn><abstract>A novel fluorescence immunoassay based on MnO
nanoflowers loading multicolor quantum dots and glutathione destroying MnO
nanoflowers to release quantum dots combined with magnetic separation is developed for rapid, ultra-sensitive, and simultaneous quantitative detection of ochratoxin A, aflatoxin B
, fumonisin B
, and zearalenone in cereal samples. The test linear range of assay is from 0.001 to 200 μg L
. The limit of detection for ochratoxin A, aflatoxin B
, fumonisin B
, and zearalenone is 0.0001 μg L
, 0.0001 μg L
, 0.0003 μg L
, and 0.0001 μg L
, respectively. The simultaneous detection of four mycotoxins can be achieve within 30 min. The test results of four mycotoxins in the incurred corn, rice, and oat samples have been confirmed by ultra-performance liquid chromatography tandem mass spectrometry, the differences between results are considered no significantly different (p > 0.05). This multiplexed test scheme has provided a potential analysis strategy for multiple food risk factors.</abstract><cop>England</cop><pmid>37037114</pmid><doi>10.1016/j.foodchem.2023.136099</doi></addata></record> |
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language | eng |
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source | MEDLINE; Elsevier ScienceDirect Journals |
subjects | Aflatoxin B1 - analysis Edible Grain - chemistry Food Contamination - analysis Immunoassay - methods Limit of Detection Manganese Compounds Mycotoxins - analysis Oxides Zearalenone - analysis |
title | A fluorescence immunoassay based on GSH destroying MnO 2 @QDs for the simultaneous ultrasensitive detection of four mycotoxins in cereals |
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