Study of dose dependence on density in planar 3D-printed applicators for HDR Ir 192 surface brachytherapy

This paper describes a method to evaluate the influence of 3D printed plesiotherapy applicators densities in the most clinically relevant dosimetric planes of these brachytherapy treatments. Studied densities range goes from that of water to that of air including the intermediate applicators densities made of acrylonitrile butadiene styrene and polylactic acid, materials used as Fused Deposition Modelling (FDM) filaments. All applicators were manufactured by means of FDM 3D printing and a special empty applicator of ABS walls was designed to be filled with water or air. In each of these applicators, the values of the dose and gamma index at the surface and at the prescription depth were measured in clinical conditions, using EBT films. Analysis of results allow us to conclude that the influence of the applicators density on the dose value in the studied materials depends on the distance at which the dose is measured. Thus, at the prescription depth no influence is observed, however this influence becomes noticeable near the surface of the applicators with dose differences of more than 10% for densities close to 0.4 g/cm . Therefore, the density of FDM manufactured applicators should be taken into account when calculating surface dose for low density applicators, as variations caused by density can have clinical implications because is the surface dose that is associated with the toxicity of brachytherapy skin treatments.