MicroRNA-155-5p Aggravates Adriamycin-Induced Focal Segmental Glomerulosclerosis through Targeting Nrf2

Introduction: Focal segmental glomerulosclerosis (FSGS) is characterized by focal and segmental obliteration of glomerular capillary tufts with increased matrix and usually associated with nephrotic range proteinuria. FSGS is a huge burden to society; however, the mechanisms remain unclear and treat...

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Veröffentlicht in:	Nephron (2015) 2023-03, Vol.147 (2), p.108-119
Hauptverfasser:	Liu, Guoyong, He, Liyu, Yang, Xiaomeng, Tang, Lingling, Shi, Wei, She, Jian, Wei, Jiali
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antagomirs - therapeutic use Doxorubicin - toxicity Experimental Nephrology and Genetics: Research Article Fibrosis Glomerulosclerosis, Focal Segmental - chemically induced Glomerulosclerosis, Focal Segmental - drug therapy Glomerulosclerosis, Focal Segmental - genetics Inflammation Mice MicroRNAs NF-E2-Related Factor 2 - genetics NF-E2-Related Factor 2 - metabolism NF-E2-Related Factor 2 - therapeutic use
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