Hemodynamic response to different set configurations of a moderate-load resistance exercise

We aimed to determine the cardiovascular responses to two different set configuration resistance-exercise protocols during a knee extension composed of 40 repetitions with a 15RM load and a total resting time of 360 seconds. Twenty-four healthy sport science students randomly performed two sessions: (a) a long set configuration session (LSC: 4 sets of 10 repetitions with 2 min rest between sets) and (b) a short set configuration session (SSC: 8 sets of 5 repetitions with 51 s rest between sets). Before and during exercise, peak and mean values of heart rate, blood pressure, rate pressure product, and pulse pressure were obtained. Results showed that both protocols increased the overall peak and mean blood pressure values (p < 0.001). However, LSC entailed a higher peak blood pressure response at the last set (p = 0.041) and an increase throughout the first 30 repetitions (p ≤ 0.007), while SSC kept steady after the first 20 repetitions. Additionally, LSC caused higher overall peak and mean heart rate and rate pressure product values (p ≤ 0.003). Summarily, although both protocols raised blood pressure, SSC reduced the extent of the pressure and chronotropic response during resistance exercise.