Bioactive natural products from Bacteroidetes

Covering: up to end of January 2022 Bacteria representing the phylum Bacteroidetes produce a diverse range of natural products, including polyketides, peptides and lactams. Here, we discuss unique aspects of the bioactive compounds discovered thus far, and the corresponding biosynthetic pathways if...

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Veröffentlicht in:Natural product reports 2022-05, Vol.39 (5), p.145-165
Hauptverfasser: Brinkmann, Stephan, Spohn, Marius S, Schäberle, Till F
Format: Artikel
Sprache:eng
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Zusammenfassung:Covering: up to end of January 2022 Bacteria representing the phylum Bacteroidetes produce a diverse range of natural products, including polyketides, peptides and lactams. Here, we discuss unique aspects of the bioactive compounds discovered thus far, and the corresponding biosynthetic pathways if known, providing a comprehensive overview of the Bacteroidetes as a natural product reservoir. The bacterial phylum Bacteroidetes harbors promising natural product producers. This review summarizes the bioactive compounds known to date and provides an overview if biosynthesis is elucidated and/or chemical synthesis is achieved.
ISSN:0265-0568
1460-4752
DOI:10.1039/d1np00072a