Impact of Obstructive Sleep Apnea on Gestational Diabetes Mellitus

Obstructive sleep apnea (OSA) increases the risk of type 2 diabetes, and hyperinsulinemia. Pregnancy increases the risk of OSA; however, the relationship between OSA and gestational diabetes mellitus (GDM) is unclear. We aimed (1) to evaluate OSA prevalence in GDM patients; (2) to assess the associa...

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Veröffentlicht in:Archivos de bronconeumología (English ed.) 2022-03, Vol.58 (3), p.219
Hauptverfasser: Alonso-Fernández, Alberto, Cerdá Moncadas, María, Álvarez Ruiz De Larrinaga, Ainhoa, Sánchez Barón, Andrés, Codina Marcet, Mercedes, Rodríguez Rodríguez, Paula, Gil Gómez, Ana Victoria, Giménez Carrero, María P, Pía Martínez, Carla, Cubero Marín, José Pablo, de la Peña, Mónica, Barceló, Antonia, Morell-Garcia, Daniel, Pierola, Javier, Peña Zarza, José Antonio, Durán Cantolla, Joaquín, Marín Trigo, José María, Soriano, Joan B, García-Río, Francisco
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Sprache:eng
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Zusammenfassung:Obstructive sleep apnea (OSA) increases the risk of type 2 diabetes, and hyperinsulinemia. Pregnancy increases the risk of OSA; however, the relationship between OSA and gestational diabetes mellitus (GDM) is unclear. We aimed (1) to evaluate OSA prevalence in GDM patients; (2) to assess the association between OSA and GDM; and (3) to determine the relationships between sleep parameters with insulin resistance (IR). A total of 177 consecutive women (89 with GDM, 88 controls) in the third trimester of pregnancy underwent a hospital polysomnography. OSA was defined when the apnea-hypopnea index (AHI) was ≥5h . Patients with GDM had higher pregestational body mass index (BMI) and neck circumference than controls, but no differences in snoring or OSA-symptoms, or AHI (3.2±6.0 vs. 1.9±2.7h , p=.069). OSA prevalence was not significantly different in both groups. We did not identify OSA as a GDM risk factor in the crude analysis 1.65 (95%CI: 0.73-3.77; p=.232). Multiple regression showed that total sleep time (TST), TST spent with oxygen saturation
ISSN:1579-2129
DOI:10.1016/j.arbres.2021.05.005