Rational design of a self-assembled surfactant film in nanopipettes: combined fluorescence and electrochemical sensing

Herein, a generalizable method based on the formation of a self-assembled surfactant film was reported to build a nanopipette system. Using this nanopipette, it was found that arginine metabolism shows an age-related difference in Alzheimer's disease. We developed a facile and generalizable nanopipette functionalization method based on the formation of a self-assembled surfactant film.