Mycotoxins produced by Aspergillus fumigatus isolated from silage

Results are presented which show that Aspergillus fumigatus was one of the predominant fungi contaminating moldy silage. Growth of A. fumigatus on silage appeared to depend on a preliminary aerobic fermentation by other natural microflora in silage. The clavine alkaloid, fumigaclavine A, and a new c...

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Veröffentlicht in:	Annales de la nutrition et de l'alimentation 1977, Vol.31 (4/6), p.685-691
Hauptverfasser:	Cole, R.J, Kirksey, J.W, Dorner, J.W, Wilson, D.M, Johnson, J. Jr, Bedell, D, Springer, J.P, Chexal, K.K, Clardy, J, Cox, R.H
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal Feed Animals Aspergillus fumigatus - metabolism Chickens feeds Food Microbiology Lethal Dose 50 Male Mycotoxins - biosynthesis Mycotoxins - isolation & purification PREMIÈRE PARTIE: DISTRIBUTION, MYCOTOXYNOGENÈSE MYCOTOXINES RECEMMENT DÉCOUVERTES Silage
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Zusammenfassung:	Results are presented which show that Aspergillus fumigatus was one of the predominant fungi contaminating moldy silage. Growth of A. fumigatus on silage appeared to depend on a preliminary aerobic fermentation by other natural microflora in silage. The clavine alkaloid, fumigaclavine A, and a new clavine alkaloid designated fumigaclavine were produced by A. fumigatus. The LD₅₀ of fumigaclavine C was approximately 150 mg/kg oral dose in dayold cockerels.
ISSN:	0003-4037