A pan-cancer signature for dysfunctional T cells

A preprint by Jerby-Arnon et al. uses a novel algorithm for scRNAseq data to describe a pan-cancer programme for dysfunctional tumour-infiltrating lymphocytes that predicts response to immune checkpoint blockade therapy.

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Bibliographische Detailangaben
Veröffentlicht in:	Nature reviews. Immunology 2022-02, Vol.22 (2), p.74-74
Hauptverfasser:	Ruffin, Nicolas, Guerreiro-Cacais, Andre Ortlieb
Format:	Artikel
Sprache:	eng
Schlagworte:	631/250/1619/554/1834 631/250/580 Biomedical and Life Sciences Biomedicine Immune checkpoint Immunology Journal Club Life Sciences & Biomedicine Lymphocytes Lymphocytes T Medicin och hälsovetenskap Science & Technology Tumors
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Beschreibung
Zusammenfassung:	A preprint by Jerby-Arnon et al. uses a novel algorithm for scRNAseq data to describe a pan-cancer programme for dysfunctional tumour-infiltrating lymphocytes that predicts response to immune checkpoint blockade therapy.
ISSN:	1474-1733 1474-1741 1474-1741
DOI:	10.1038/s41577-021-00672-2