18 F-FET-PET-guided gross total resection improves overall survival in patients with WHO grade III/IV glioma: moving towards a multimodal imaging-guided resection

PET using radiolabeled amino acid [ F]-fluoro-ethyl- -tyrosine (FET-PET) is a well-established imaging modality for glioma diagnostics. The biological tumor volume (BTV) as depicted by FET-PET often differs in volume and location from tumor volume of contrast enhancement (CE) in MRI. Our aim was to...

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Veröffentlicht in:	Journal of neuro-oncology 2021-10, Vol.155 (1), p.71
Hauptverfasser:	Ort, Jonas, Hamou, Hussam Aldin, Kernbach, Julius M, Hakvoort, Karlijn, Blume, Christian, Lohmann, Philipp, Galldiks, Norbert, Heiland, Dieter Henrik, Mottaghy, Felix M, Clusmann, Hans, Neuloh, Georg, Langen, Karl-Josef, Delev, Daniel
Format:	Artikel
Sprache:	eng
Schlagworte:	Brain Neoplasms - diagnostic imaging Brain Neoplasms - genetics Brain Neoplasms - surgery Glioblastoma Glioma - diagnostic imaging Glioma - genetics Glioma - surgery Humans Magnetic Resonance Imaging Multimodal Imaging Positron-Emission Tomography - methods Retrospective Studies Tyrosine World Health Organization
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Zusammenfassung:	PET using radiolabeled amino acid [ F]-fluoro-ethyl- -tyrosine (FET-PET) is a well-established imaging modality for glioma diagnostics. The biological tumor volume (BTV) as depicted by FET-PET often differs in volume and location from tumor volume of contrast enhancement (CE) in MRI. Our aim was to investigate whether a gross total resection of BTVs defined as
ISSN:	1573-7373
DOI:	10.1007/s11060-021-03844-1