CLINICAL EFFICACY OF FLOMOXEF IN THE FIELD OF PEDIATRICS

A new oxacephem antibiotic, flomoxef sodium (FMOX, 6315-S), was studied for its clinical efficacy in the field of pediatrics. The treated patients were infants and children ranging from 6 months to 14 years old suffering from bacterial pneumonia in 3 cases, acute tonsillitis in 2 cases, acute entero...

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Veröffentlicht in:	Japanese journal of antibiotics 1987, Vol.40(8), pp.1496-1501
Hauptverfasser:	OGURA, Hideo, KUBOTA, HARUO, MURAKAMI, NOBUYUKI, TOMODA, TAKASHI, HAMADA, FUMIHIKO, MATSUMOTO, KENJI, ARAKI, KUMIKO, OGURA, YUKIKO, KURASHIGE, TAKANOBU, KITAMURA, ISAMU, HAYASHI, YUKO, TANI, JUNKICHI
Format:	Artikel
Sprache:	jpn
Schlagworte:	Adolescent Age Factors Bacteria - isolation & purification Bacterial Infections - drug therapy Bacterial Infections - microbiology Cephalosporins - adverse effects Cephalosporins - therapeutic use Child Child, Preschool Drug Evaluation Female Humans Infant Male
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Zusammenfassung:	A new oxacephem antibiotic, flomoxef sodium (FMOX, 6315-S), was studied for its clinical efficacy in the field of pediatrics. The treated patients were infants and children ranging from 6 months to 14 years old suffering from bacterial pneumonia in 3 cases, acute tonsillitis in 2 cases, acute enterocolitis in 2 cases, and cellulitis and urinary tract infection in 1 case each, a total of 9 cases. FMOX was administered at (levels of) 57-150 mg/kg in daily dose with durations of treatment ranging from 5 to 18 days. Clinical efficacies of good or excellent results were obtained in all cases (excellent in 4, good in 5). As an adverse reaction, eosinophilia was observed in 1 patient. This elevation is, however, normalized with the cessation of the treatment.
ISSN:	0368-2781 2186-5477
DOI:	10.11553/antibiotics1968b.40.1496