Recent progress in the nitration of arenes and alkenes

Nitro compounds are a predominant class of synthetic intermediates and building blocks for the preparation of a wide range of nitrogen-containing compounds in the chemical industry. As such, impressive progress has been currently made in the nitration of aromatics and olefins with excellent function...

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Veröffentlicht in:Organic & biomolecular chemistry 2021-06, Vol.19 (22), p.4835-4851
Hauptverfasser: Qian, Yu-En, Zheng, Lan, Xiang, Hao-Yue, Yang, Hua
Format: Artikel
Sprache:eng
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Zusammenfassung:Nitro compounds are a predominant class of synthetic intermediates and building blocks for the preparation of a wide range of nitrogen-containing compounds in the chemical industry. As such, impressive progress has been currently made in the nitration of aromatics and olefins with excellent functional group tolerance and site-selectivity. In this mini review, we intend to highlight the regiospecific nitration of arenes and alkenes in various reaction systems. The involved mechanisms are discussed as well. This mini review summarizes the recent advances in the regiospecific nitrations of arenes and alkenes based on the structural features of substrates.
ISSN:1477-0520
1477-0539
DOI:10.1039/d1ob00384d