Lupus anticoagulant single positivity at acute phase is not associated with venous thromboembolism or in-hospital mortality in COVID-19

Antiphospholipid antibodies (APA) clinical relevance in COVID-19 is controversial. We aimed to investigate the prevalence and prognostic value of conventional and non-conventional APA in COVID-19 patients. This study was a multi-centric, prospective observational French cohort of patients hospitaliz...

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Veröffentlicht in:	Arthritis & rheumatology (Hoboken, N.J.) N.J.), 2021-04
Hauptverfasser:	Gendron, Nicolas, Dragon-Durey, Marie-Agnès, Chocron, Richard, Darnige, Luc, Jourdi, Georges, Philippe, Aurélien, Chenevier-Gobeaux, Camille, Hadjadj, Jérôme, Duchemin, Jérôme, Khider, Lina, Yatim, Nader, Goudot, Guillaume, Krzisch, Daphné, Debuc, Benjamin, Mauge, Laetitia, Levasseur, Françoise, Pene, Frédéric, Boussier, Jeremy, Sourdeau, Elise, Brichet, Julie, Ochat, Nadège, Goulvestre, Claire, Peronino, Christophe, Szwebel, Tali-Anne, Pages, Franck, Gaussem, Pascale, Samama, Charles-Marc, Cheurfa, Cherifa, Planquette, Benjamin, Sanchez, Olivier, Diehl, Jean-Luc, Mirault, Tristan, Fontenay, Michaela, Terrier, Benjamin, Smadja, David M
Format:	Artikel
Sprache:	eng
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Zusammenfassung:	Antiphospholipid antibodies (APA) clinical relevance in COVID-19 is controversial. We aimed to investigate the prevalence and prognostic value of conventional and non-conventional APA in COVID-19 patients. This study was a multi-centric, prospective observational French cohort of patients hospitalized for COVID-19 suspicion. 249 patients were hospitalized for suspected COVID-19, including 154 with confirmed COVID-19 and 95 not confirmed. We found a significant increase in lupus anticoagulant (LA) positivity among COVID-19 positive patients (60.9% versus 23.7% in non-COVID19 patients, p
ISSN:	2326-5205
DOI:	10.1002/art.41777