Mortality analysis of obstructive sleep apnea syndrome cohort receiving positive airway pressure treatment: a 6-year follow-up
Obstructive Sleep apne syndrome is a disease with high morbidity and mortality. The aim of this study was to investigate the conditions affecting the mortality of patients diagnosed with OSAS at six year follow up. 970 patients who admitted to Sleep laboratory between 2011-2013 were evaluated retros...
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Veröffentlicht in: | The aging male 2020-12, Vol.23 (5), p.1046-1051 |
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description | Obstructive Sleep apne syndrome is a disease with high morbidity and mortality. The aim of this study was to investigate the conditions affecting the mortality of patients diagnosed with OSAS at six year follow up.
970 patients who admitted to Sleep laboratory between 2011-2013 were evaluated retrospectively. 74 patients whose mortality data could not be accessed through the system were excluded. The patients who died until April 2019 were compared with the surviving group in terms of demographic, clinical, comorbidities and polysomnographic findings.
Total 47 patients who died were older, had higher BMI, AHI and ODI values, lower minimum oxygen saturations compared with the survival group (p 50/h (2.19, 1.19-1.4.05) were reported.
This study showed that OSAS increases the risk of death accompanied by CAD and COPD. It has also been shown that patients with higher AHI (AHI > 50/h) values die more. Therefore, it may be useful to classify the AHI> 50/h group as very severe OSAS instead of severe OSAS. |
doi_str_mv | 10.1080/13685538.2019.1660959 |
format | Article |
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970 patients who admitted to Sleep laboratory between 2011-2013 were evaluated retrospectively. 74 patients whose mortality data could not be accessed through the system were excluded. The patients who died until April 2019 were compared with the surviving group in terms of demographic, clinical, comorbidities and polysomnographic findings.
Total 47 patients who died were older, had higher BMI, AHI and ODI values, lower minimum oxygen saturations compared with the survival group (p < .001). In the Cox-hazard regression analysis, BMI (hazard ratio (HR), 1.08; 95% CI, 1.04-1.12), age (1.12, 1.08-1.15), accompanying COPD (2.19, 1.08-4.43), accompanying CAD (2.76, 1.34-5.67) and AHI of >50/h (2.19, 1.19-1.4.05) were reported.
This study showed that OSAS increases the risk of death accompanied by CAD and COPD. It has also been shown that patients with higher AHI (AHI > 50/h) values die more. Therefore, it may be useful to classify the AHI> 50/h group as very severe OSAS instead of severe OSAS.</description><identifier>ISSN: 1368-5538</identifier><identifier>EISSN: 1473-0790</identifier><identifier>DOI: 10.1080/13685538.2019.1660959</identifier><identifier>PMID: 33878843</identifier><language>eng</language><publisher>England: Taylor & Francis</publisher><subject>Age groups ; Aging ; apnea hypopnea index ; Body mass index ; cardiovasculer disease ; Chronic obstructive pulmonary disease ; Cohort Studies ; Comorbidity ; COPD ; Follow-Up Studies ; Health risks ; Humans ; Mortality ; Obstructive sleep apnea ; Respiratory therapy ; Retrospective Studies ; Sleep ; Sleep apnea ; Sleep Apnea, Obstructive - complications ; Sleep Apnea, Obstructive - therapy</subject><ispartof>The aging male, 2020-12, Vol.23 (5), p.1046-1051</ispartof><rights>2019 Informa UK Limited, trading as Taylor & Francis Group 2019</rights><rights>2019 Informa UK Limited, trading as Taylor & Francis Group</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c389t-f5c08ff3211acf0f972fc7a23e359275659bf241d53b453d17071a1e3c8346393</cites><orcidid>0000-0002-2916-5824</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33878843$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Çetintaş Afşar, Gülgün</creatorcontrib><creatorcontrib>Yıldız, Tekin</creatorcontrib><creatorcontrib>Sogukpınar, Ozlem</creatorcontrib><creatorcontrib>Saraç, Sema</creatorcontrib><creatorcontrib>Oztin Güven, Ayşem</creatorcontrib><creatorcontrib>Saltürk, Cüneyt</creatorcontrib><title>Mortality analysis of obstructive sleep apnea syndrome cohort receiving positive airway pressure treatment: a 6-year follow-up</title><title>The aging male</title><addtitle>Aging Male</addtitle><description>Obstructive Sleep apne syndrome is a disease with high morbidity and mortality. The aim of this study was to investigate the conditions affecting the mortality of patients diagnosed with OSAS at six year follow up.
970 patients who admitted to Sleep laboratory between 2011-2013 were evaluated retrospectively. 74 patients whose mortality data could not be accessed through the system were excluded. The patients who died until April 2019 were compared with the surviving group in terms of demographic, clinical, comorbidities and polysomnographic findings.
Total 47 patients who died were older, had higher BMI, AHI and ODI values, lower minimum oxygen saturations compared with the survival group (p < .001). In the Cox-hazard regression analysis, BMI (hazard ratio (HR), 1.08; 95% CI, 1.04-1.12), age (1.12, 1.08-1.15), accompanying COPD (2.19, 1.08-4.43), accompanying CAD (2.76, 1.34-5.67) and AHI of >50/h (2.19, 1.19-1.4.05) were reported.
This study showed that OSAS increases the risk of death accompanied by CAD and COPD. It has also been shown that patients with higher AHI (AHI > 50/h) values die more. Therefore, it may be useful to classify the AHI> 50/h group as very severe OSAS instead of severe OSAS.</description><subject>Age groups</subject><subject>Aging</subject><subject>apnea hypopnea index</subject><subject>Body mass index</subject><subject>cardiovasculer disease</subject><subject>Chronic obstructive pulmonary disease</subject><subject>Cohort Studies</subject><subject>Comorbidity</subject><subject>COPD</subject><subject>Follow-Up Studies</subject><subject>Health risks</subject><subject>Humans</subject><subject>Mortality</subject><subject>Obstructive sleep apnea</subject><subject>Respiratory therapy</subject><subject>Retrospective Studies</subject><subject>Sleep</subject><subject>Sleep apnea</subject><subject>Sleep Apnea, Obstructive - complications</subject><subject>Sleep Apnea, Obstructive - therapy</subject><issn>1368-5538</issn><issn>1473-0790</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp90T2P1DAQBuAIgbgP-AkgSzQ0WfwRxwkV6AQH0iEaqK1Z7xh8cuIwdm6Vht9O9naPgoLKUzzvjOS3ql4IvhG842-EajutVbeRXPQb0ba81_2j6lw0RtXc9PzxOq-mPqCz6iLnW86FNMY8rc6U6kzXNeq8-v0lUYEYysJghLjkkFnyLG1zodmVcIcsR8SJwTQisLyMO0oDMpd-rkFG6DDchfEHm1IO9xwC7WFhE2HOMyErhFAGHMtbBqytFwRiPsWY9vU8PaueeIgZn5_ey-r7xw_frj7VN1-vP1-9v6md6vpSe-14572SQoDz3PdGemdAKlS6l0a3ut962YidVttGq50w3AgQqFynmlb16rJ6fdw7Ufo1Yy52CNlhjDBimrOVWrRSto2RK331D71NM61_c6-01qszq9JH5SjlTOjtRGEAWqzg9lCQfSjIHgqyp4LW3MvT9nk74O5v6qGRFbw7gjD6RAPsE8WdLbDERJ5gdCFb9f8bfwCL_6Di</recordid><startdate>202012</startdate><enddate>202012</enddate><creator>Çetintaş Afşar, Gülgün</creator><creator>Yıldız, Tekin</creator><creator>Sogukpınar, Ozlem</creator><creator>Saraç, Sema</creator><creator>Oztin Güven, Ayşem</creator><creator>Saltürk, Cüneyt</creator><general>Taylor & Francis</general><general>Taylor & Francis Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-2916-5824</orcidid></search><sort><creationdate>202012</creationdate><title>Mortality analysis of obstructive sleep apnea syndrome cohort receiving positive airway pressure treatment: a 6-year follow-up</title><author>Çetintaş Afşar, Gülgün ; Yıldız, Tekin ; Sogukpınar, Ozlem ; Saraç, Sema ; Oztin Güven, Ayşem ; Saltürk, Cüneyt</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c389t-f5c08ff3211acf0f972fc7a23e359275659bf241d53b453d17071a1e3c8346393</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Age groups</topic><topic>Aging</topic><topic>apnea hypopnea index</topic><topic>Body mass index</topic><topic>cardiovasculer disease</topic><topic>Chronic obstructive pulmonary disease</topic><topic>Cohort Studies</topic><topic>Comorbidity</topic><topic>COPD</topic><topic>Follow-Up Studies</topic><topic>Health risks</topic><topic>Humans</topic><topic>Mortality</topic><topic>Obstructive sleep apnea</topic><topic>Respiratory therapy</topic><topic>Retrospective Studies</topic><topic>Sleep</topic><topic>Sleep apnea</topic><topic>Sleep Apnea, Obstructive - complications</topic><topic>Sleep Apnea, Obstructive - therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Çetintaş Afşar, Gülgün</creatorcontrib><creatorcontrib>Yıldız, Tekin</creatorcontrib><creatorcontrib>Sogukpınar, Ozlem</creatorcontrib><creatorcontrib>Saraç, Sema</creatorcontrib><creatorcontrib>Oztin Güven, Ayşem</creatorcontrib><creatorcontrib>Saltürk, Cüneyt</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>The aging male</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Çetintaş Afşar, Gülgün</au><au>Yıldız, Tekin</au><au>Sogukpınar, Ozlem</au><au>Saraç, Sema</au><au>Oztin Güven, Ayşem</au><au>Saltürk, Cüneyt</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Mortality analysis of obstructive sleep apnea syndrome cohort receiving positive airway pressure treatment: a 6-year follow-up</atitle><jtitle>The aging male</jtitle><addtitle>Aging Male</addtitle><date>2020-12</date><risdate>2020</risdate><volume>23</volume><issue>5</issue><spage>1046</spage><epage>1051</epage><pages>1046-1051</pages><issn>1368-5538</issn><eissn>1473-0790</eissn><abstract>Obstructive Sleep apne syndrome is a disease with high morbidity and mortality. The aim of this study was to investigate the conditions affecting the mortality of patients diagnosed with OSAS at six year follow up.
970 patients who admitted to Sleep laboratory between 2011-2013 were evaluated retrospectively. 74 patients whose mortality data could not be accessed through the system were excluded. The patients who died until April 2019 were compared with the surviving group in terms of demographic, clinical, comorbidities and polysomnographic findings.
Total 47 patients who died were older, had higher BMI, AHI and ODI values, lower minimum oxygen saturations compared with the survival group (p < .001). In the Cox-hazard regression analysis, BMI (hazard ratio (HR), 1.08; 95% CI, 1.04-1.12), age (1.12, 1.08-1.15), accompanying COPD (2.19, 1.08-4.43), accompanying CAD (2.76, 1.34-5.67) and AHI of >50/h (2.19, 1.19-1.4.05) were reported.
This study showed that OSAS increases the risk of death accompanied by CAD and COPD. It has also been shown that patients with higher AHI (AHI > 50/h) values die more. Therefore, it may be useful to classify the AHI> 50/h group as very severe OSAS instead of severe OSAS.</abstract><cop>England</cop><pub>Taylor & Francis</pub><pmid>33878843</pmid><doi>10.1080/13685538.2019.1660959</doi><tpages>6</tpages><orcidid>https://orcid.org/0000-0002-2916-5824</orcidid><oa>free_for_read</oa></addata></record> |
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subjects | Age groups Aging apnea hypopnea index Body mass index cardiovasculer disease Chronic obstructive pulmonary disease Cohort Studies Comorbidity COPD Follow-Up Studies Health risks Humans Mortality Obstructive sleep apnea Respiratory therapy Retrospective Studies Sleep Sleep apnea Sleep Apnea, Obstructive - complications Sleep Apnea, Obstructive - therapy |
title | Mortality analysis of obstructive sleep apnea syndrome cohort receiving positive airway pressure treatment: a 6-year follow-up |
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