Tumour grade and primary site predict patterns of recurrence and survival in patients with resected gastroenteropancreatic neuroendocrine tumors

Tumour grade and primary site predict patterns of recurrence and survival in patients with resected gastroenteropancreatic neuroendocrine tumors

Patterns of recurrence help to inform surveillance of patients with resected gastroenteropancreatic neuroendocrine tumors (GEP-NETs). Patients with GEP-NETs in British Columbia, Canada (2004–2015) were reviewed. Associations between tumor characteristics, recurrence and survival were analyzed. Among...

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Veröffentlicht in:The American journal of surgery 2021-06, Vol.221 (6), p.1141-1149
Hauptverfasser: Watanabe, Akie, Yip, Lily, Hamilton, Trevor D., Loree, Jonathan M., Stuart, Heather C.
Format: Artikel
Sprache:eng
Schlagworte:
Age
Gastroenteropancreatic neuroendocrine tumors
Life Sciences & Biomedicine
Liver
Metastasis
Neuroendocrine tumors
Pancreas
Patients
Peritoneum
Primary tumor location
Recurrence patterns
Science & Technology
Small intestine
Surgery
Surveillance
Surveillance guidelines
Survival
Tumor grade
Tumors
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Zusammenfassung:Patterns of recurrence help to inform surveillance of patients with resected gastroenteropancreatic neuroendocrine tumors (GEP-NETs). Patients with GEP-NETs in British Columbia, Canada (2004–2015) were reviewed. Associations between tumor characteristics, recurrence and survival were analyzed. Among 759 patients, 41%, 25%, and 17% had grade 1, 2, and 3 disease, respectively. 387 patients had R0/R1 resections, of which 30% recurred (median 25 months). 5-year incidence of recurrence was 22% (grade 1), 46% (grade 2), and 59% (grade 3) (p 
ISSN:0002-9610
1879-1883
DOI:10.1016/j.amjsurg.2021.03.027