Factors Associated With Being Overweight and Obesity in People Living With Human Immunodeficiency Virus on Antiretroviral Therapy: Socioclinical, Inflammation, and Metabolic Markers

Factors Associated With Being Overweight and Obesity in People Living With Human Immunodeficiency Virus on Antiretroviral Therapy: Socioclinical, Inflammation, and Metabolic Markers

Abstract Background We investigated the association between socioclinical, inflammatory, and metabolic markers and weight gain in people with human immunodeficiency virus (HIV) on combination antiretroviral therapy (cART). Methods Individuals from the COPANA cohort of normal weight (body mass index...

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Veröffentlicht in:The Journal of infectious diseases 2021-11, Vol.224 (9), p.1570-1580
Hauptverfasser: Goupil de Bouillé, Jeanne, Vigouroux, Corinne, Plessis, Lorraine, Ghislain, Mathilde, Teglas, Jean-Paul, Boufassa, Faroudy, Goujard, Cécile, Vignes, Dorothée, Bouchaud, Olivier, Salmon, Dominique, Meyer, Laurence, Abgrall, Sophie
Format: Artikel
Sprache:eng
Schlagworte:
Adiponectin
Antiretroviral drugs
Antiretroviral therapy
Antiretroviral Therapy, Highly Active
Body mass index
Body weight
Body weight gain
C-reactive protein
CD14 antigen
CD16 antigen
Cell activation
CXCL10 protein
Drug therapy
Female
HIV
HIV Infections - complications
HIV Infections - drug therapy
Human immunodeficiency virus
Humans
Immune system
Immunology
Infectious Diseases
Inflammation
Insulin
Interleukin 6
Leptin
Life Sciences & Biomedicine
Male
Metabolism
Microbiology
Monocytes
Obesity
Obesity - complications
Overweight
Regression analysis
Science & Technology
Tumor necrosis factor
Tumor necrosis factor receptor 2
Tumor necrosis factor receptors
Tumor necrosis factor-TNF
Weight Gain
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Zusammenfassung:Abstract Background We investigated the association between socioclinical, inflammatory, and metabolic markers and weight gain in people with human immunodeficiency virus (HIV) on combination antiretroviral therapy (cART). Methods Individuals from the COPANA cohort of normal weight (body mass index [BMI], 18.5–24.9 [ calculated as weight in kilograms divided by height in meters squared) at cART initiation who achieved virological suppression (viral load,
ISSN:0022-1899
1537-6613
DOI:10.1093/infdis/jiab151