Vessel flow void sign and hyperintense vessel sign on FLAIR images distinguish between MELAS and AIS

•The new scoring criterion based on FLAIR images differentiates MELAS from AIS.•The new scoring criterion differentiate MELAS from ALS. This study aimed to evaluate the sensitivity and specificity of the vessel signs, including the Vessel Flow Void Sign (VFVS) and the Hyperintense Vessel Sign (HVS)...

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Veröffentlicht in:	Mitochondrion 2021-05, Vol.58, p.131-134
Hauptverfasser:	Chong, Li, Zhenzhou, Lin, Daokun, Ren, Yuankui, Wu, Hui, Zheng, Chao, Yuan, Yafang, Hu, Haishan, Jiang
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult AIS Brain MRI Cell Biology Cerebrovascular Circulation Diagnosis, Differential Female Genetics & Heredity Humans Ischemic Stroke - diagnostic imaging Ischemic Stroke - physiopathology Life Sciences & Biomedicine Magnetic Resonance Angiography Male MELAS MELAS Syndrome - diagnostic imaging MELAS Syndrome - physiopathology Middle Aged Science & Technology Stroke-like episodes Vessel flow void sign
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Zusammenfassung:	•The new scoring criterion based on FLAIR images differentiates MELAS from AIS.•The new scoring criterion differentiate MELAS from ALS. This study aimed to evaluate the sensitivity and specificity of the vessel signs, including the Vessel Flow Void Sign (VFVS) and the Hyperintense Vessel Sign (HVS) in Fluid Attenuated Inversion Recovery (FLAIR) images during the differentiation of Mitochondrial Encephalopathy, Lactic Acidosis, and Stroke-like Episodes (MELAS) in Acute Ischemic Stroke (AIS). Magnetic Resonance Imaging (MRI) scans of 13 MELAS and 20 AIS patients were obtained during the acute stage of the diseases (median time to scan 1.5 scores were prone to be MELAS, while patients with
ISSN:	1567-7249 1872-8278
DOI:	10.1016/j.mito.2021.02.015