Benefit of transaminase elevations in establishing functional cure of HBV infection during nap‐based combination therapy

Treatment of HBV infection with nucleic acid polymers and pegIFN is accompanied by transaminase elevations in 95% of participants. HBV viral rebound, partial cure (HBV DNA

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of viral hepatitis 2021-05, Vol.28 (5), p.817-825
Hauptverfasser:	Bazinet, Michel, Pântea, Victor, Placinta, Gheorghe, Moscalu, Iurie, Cebotarescu, Valentin, Cojuhari, Lilia, Jimbei, Pavlina, Iarovoi, Liviu, Smesnoi, Valentina, Musteata, Tatiana, Jucov, Alina, Dittmer, Ulf, Krawczyk, Adalbert, Vaillant, Andrew
Format:	Artikel
Sprache:	eng
Schlagworte:	ALT AST GGT flare Combination therapy Deoxyribonucleic acid DNA Gastroenterology & Hepatology HBsAg HBV functional cure Hepatitis B surface antigen Infectious Diseases Life Sciences & Biomedicine nucleic acid polymer Science & Technology Transaminase Virology
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Treatment of HBV infection with nucleic acid polymers and pegIFN is accompanied by transaminase elevations in 95% of participants. HBV viral rebound, partial cure (HBV DNA
ISSN:	1352-0504 1365-2893
DOI:	10.1111/jvh.13483