Recurrence after radical and partial nephrectomy in high complex renal tumor using propensity score matched analysis

We evaluated the recurrence after radical and partial nephrectomy in patients with RENAL nephrometry score [RENAL] ≥ 10. A total of 474 patients (radical nephrectomy [RN, n = 236] & partial nephrectomy [PN, n = 238]) in a single tertiary referral institution from December 2003 to December 2019 w...

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Veröffentlicht in:Scientific reports 2021-02, Vol.11 (1), p.2919-2919, Article 2919
Hauptverfasser: Kim, Hwanik, Kim, Jung Kwon, Ye, Changhee, Choi, Joon Hyeok, Lee, Hakmin, Oh, Jong Jin, Lee, Sangchul, Hong, Sung Kyu, Byun, Seok-Soo
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Sprache:eng
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Zusammenfassung:We evaluated the recurrence after radical and partial nephrectomy in patients with RENAL nephrometry score [RENAL] ≥ 10. A total of 474 patients (radical nephrectomy [RN, n = 236] & partial nephrectomy [PN, n = 238]) in a single tertiary referral institution from December 2003 to December 2019 were assessed. Functional outcomes, defined as estimated glomerular filtration rate changes, relapse pattern, recurrence-free survival (RFS), cancer-specific survival (CSS), and overall survival (OS) were evaluated using propensity score-matched analysis. The predictors of recurrence and survival were assessed by Cox-regression analysis. 44 patients in the RN group and 88 in the PN group were included without significant differences in preoperative clinical factors after matching. The PN patients achieved significantly higher renal function preservation rates (p 
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-021-82700-8