Traditional Chinese medicine (TCM) as a source of new anticancer drugs
Covering: up to July 2020 Drugs derived from traditional Chinese medicine (TCM) include both single chemical entities and multi-component preparations. Drugs of both types play a significant role in the healthcare system in China, but are not well-known outside China. The research and development pr...
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| Veröffentlicht in: | Natural product reports 2021-09, Vol.38 (9), p.1618-1633 |
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| creator | Yao, Chang-liang Zhang, Jian-qing Li, Jia-yuan Wei, Wen-long Wu, Shi-fei Guo, De-an |
| description | Covering: up to July 2020
Drugs derived from traditional Chinese medicine (TCM) include both single chemical entities and multi-component preparations. Drugs of both types play a significant role in the healthcare system in China, but are not well-known outside China. The research and development process, the molecular mechanisms of action, and the clinical evaluation associated with some exemplificative anticancer drugs based on TCM are discussed, along with their potential of integration in western medicine.
Drugs derived from traditional Chinese medicines (TCM) include both single chemical entities and multi-component preparations. |
| doi_str_mv | 10.1039/d0np00057d |
| format | Article |
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Drugs derived from traditional Chinese medicine (TCM) include both single chemical entities and multi-component preparations. Drugs of both types play a significant role in the healthcare system in China, but are not well-known outside China. The research and development process, the molecular mechanisms of action, and the clinical evaluation associated with some exemplificative anticancer drugs based on TCM are discussed, along with their potential of integration in western medicine.
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Drugs derived from traditional Chinese medicine (TCM) include both single chemical entities and multi-component preparations. Drugs of both types play a significant role in the healthcare system in China, but are not well-known outside China. The research and development process, the molecular mechanisms of action, and the clinical evaluation associated with some exemplificative anticancer drugs based on TCM are discussed, along with their potential of integration in western medicine.
Drugs derived from traditional Chinese medicines (TCM) include both single chemical entities and multi-component preparations.</description><subject>Antineoplastic Agents - pharmacology</subject><subject>Antineoplastic drugs</subject><subject>Antitumor agents</subject><subject>Cancer</subject><subject>Chinese medicine</subject><subject>Drug Screening Assays, Antitumor</subject><subject>Drugs</subject><subject>Drugs, Chinese Herbal - pharmacology</subject><subject>Herbal medicine</subject><subject>Humans</subject><subject>Medicine, Chinese Traditional</subject><subject>Molecular modelling</subject><subject>R&D</subject><subject>Research & development</subject><subject>Traditional Chinese medicine</subject><issn>0265-0568</issn><issn>1460-4752</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpd0c9LwzAUwPEgipvTi3cl4GUK1ZemSdujdE6F-eMwzyVNXrWja2fSIv73Zm4qeEogHx68bwg5ZnDJgKdXBpoVAIjY7JAhiyQEUSzCXTKEUIoAhEwG5MC5BQBjsZT7ZMC5YCyV6ZBM51aZqqvaRtU0e6sadEiXaCrtr3Q8zx7OqXJUUdf2ViNtS9rgB1VNV2nVaLTU2P7VHZK9UtUOj7bniLxMb-bZXTB7ur3PrmeB5nHSBUIxmUosQMWh0KWRPCm4lokuIx2VSjGBOkIeMmk0QxObpGQcOS8iYULQwEdkvJm7su17j67Ll5XTWNeqwbZ3eRglPGFpFK7p2T-68Cv4Nb0Svo8vF6deXWyUtq1zFst8Zaulsp85g3xdN5_A4_N33YnHp9uRfeEb_dKfnB6cbIB1-vf173v4F64IfNk</recordid><startdate>20210923</startdate><enddate>20210923</enddate><creator>Yao, Chang-liang</creator><creator>Zhang, Jian-qing</creator><creator>Li, Jia-yuan</creator><creator>Wei, Wen-long</creator><creator>Wu, Shi-fei</creator><creator>Guo, De-an</creator><general>Royal Society of Chemistry</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>7T7</scope><scope>7TM</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-9307-3676</orcidid></search><sort><creationdate>20210923</creationdate><title>Traditional Chinese medicine (TCM) as a source of new anticancer drugs</title><author>Yao, Chang-liang ; Zhang, Jian-qing ; Li, Jia-yuan ; Wei, Wen-long ; Wu, Shi-fei ; Guo, De-an</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c378t-5a1696eb0a725cfd638b3c68cf4c4faa15ec4e3216dc1ed7d8f13e33b45d20c03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Antineoplastic Agents - pharmacology</topic><topic>Antineoplastic drugs</topic><topic>Antitumor agents</topic><topic>Cancer</topic><topic>Chinese medicine</topic><topic>Drug Screening Assays, Antitumor</topic><topic>Drugs</topic><topic>Drugs, Chinese Herbal - pharmacology</topic><topic>Herbal medicine</topic><topic>Humans</topic><topic>Medicine, Chinese Traditional</topic><topic>Molecular modelling</topic><topic>R&D</topic><topic>Research & development</topic><topic>Traditional Chinese medicine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yao, Chang-liang</creatorcontrib><creatorcontrib>Zhang, Jian-qing</creatorcontrib><creatorcontrib>Li, Jia-yuan</creatorcontrib><creatorcontrib>Wei, Wen-long</creatorcontrib><creatorcontrib>Wu, Shi-fei</creatorcontrib><creatorcontrib>Guo, De-an</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Nucleic Acids Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Natural product reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yao, Chang-liang</au><au>Zhang, Jian-qing</au><au>Li, Jia-yuan</au><au>Wei, Wen-long</au><au>Wu, Shi-fei</au><au>Guo, De-an</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Traditional Chinese medicine (TCM) as a source of new anticancer drugs</atitle><jtitle>Natural product reports</jtitle><addtitle>Nat Prod Rep</addtitle><date>2021-09-23</date><risdate>2021</risdate><volume>38</volume><issue>9</issue><spage>1618</spage><epage>1633</epage><pages>1618-1633</pages><issn>0265-0568</issn><eissn>1460-4752</eissn><abstract>Covering: up to July 2020
Drugs derived from traditional Chinese medicine (TCM) include both single chemical entities and multi-component preparations. Drugs of both types play a significant role in the healthcare system in China, but are not well-known outside China. The research and development process, the molecular mechanisms of action, and the clinical evaluation associated with some exemplificative anticancer drugs based on TCM are discussed, along with their potential of integration in western medicine.
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| fulltext | fulltext |
| identifier | ISSN: 0265-0568 |
| ispartof | Natural product reports, 2021-09, Vol.38 (9), p.1618-1633 |
| issn | 0265-0568 1460-4752 |
| language | eng |
| recordid | cdi_pubmed_primary_33511969 |
| source | MEDLINE; Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection |
| subjects | Antineoplastic Agents - pharmacology Antineoplastic drugs Antitumor agents Cancer Chinese medicine Drug Screening Assays, Antitumor Drugs Drugs, Chinese Herbal - pharmacology Herbal medicine Humans Medicine, Chinese Traditional Molecular modelling R&D Research & development Traditional Chinese medicine |
| title | Traditional Chinese medicine (TCM) as a source of new anticancer drugs |
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