Traditional Chinese medicine (TCM) as a source of new anticancer drugs

Covering: up to July 2020 Drugs derived from traditional Chinese medicine (TCM) include both single chemical entities and multi-component preparations. Drugs of both types play a significant role in the healthcare system in China, but are not well-known outside China. The research and development pr...

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Veröffentlicht in:	Natural product reports 2021-09, Vol.38 (9), p.1618-1633
Hauptverfasser:	Yao, Chang-liang, Zhang, Jian-qing, Li, Jia-yuan, Wei, Wen-long, Wu, Shi-fei, Guo, De-an
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - pharmacology Antineoplastic drugs Antitumor agents Cancer Chinese medicine Drug Screening Assays, Antitumor Drugs Drugs, Chinese Herbal - pharmacology Herbal medicine Humans Medicine, Chinese Traditional Molecular modelling R&D Research & development Traditional Chinese medicine
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Beschreibung
Zusammenfassung:	Covering: up to July 2020 Drugs derived from traditional Chinese medicine (TCM) include both single chemical entities and multi-component preparations. Drugs of both types play a significant role in the healthcare system in China, but are not well-known outside China. The research and development process, the molecular mechanisms of action, and the clinical evaluation associated with some exemplificative anticancer drugs based on TCM are discussed, along with their potential of integration in western medicine. Drugs derived from traditional Chinese medicines (TCM) include both single chemical entities and multi-component preparations.
ISSN:	0265-0568 1460-4752
DOI:	10.1039/d0np00057d