Structural basis of GABARAP-mediated GABA A receptor trafficking and functions on GABAergic synaptic transmission

GABA receptors (GABA Rs) are the primary fast inhibitory ion channels in the central nervous system. Dysfunction of trafficking and localization of GABA Rs to cell membranes is clinically associated with severe psychiatric disorders in humans. The GABARAP protein is known to support the stability of...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Nature communications 2021-01, Vol.12 (1), p.297
Hauptverfasser: Ye, Jin, Zou, Guichang, Zhu, Ruichi, Kong, Chao, Miao, Chenjian, Zhang, Mingjie, Li, Jianchao, Xiong, Wei, Wang, Chao
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!