Chlorinated Solvents: Their Advantages, Disadvantages, and Alternatives in Organic and Medicinal Chemistry

Chlorinated solvents were once, and in many places are still, ubiquitous in chemistry laboratories. This review explores the properties that led to such widespread use, why there is now an increasing drive to minimize usage, and what alternatives are currently available.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Chemical reviews 2021-02, Vol.121 (3), p.1582-1622
Hauptverfasser: Jordan, Andrew, Stoy, Patrick, Sneddon, Helen F
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 1622
container_issue 3
container_start_page 1582
container_title Chemical reviews
container_volume 121
creator Jordan, Andrew
Stoy, Patrick
Sneddon, Helen F
description Chlorinated solvents were once, and in many places are still, ubiquitous in chemistry laboratories. This review explores the properties that led to such widespread use, why there is now an increasing drive to minimize usage, and what alternatives are currently available.
doi_str_mv 10.1021/acs.chemrev.0c00709
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmed_primary_33351588</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2492315832</sourcerecordid><originalsourceid>FETCH-LOGICAL-a418t-e58c393969056eebadc5040e4a1d9e483700edc1a45cd8d9cd75d262a25c6d753</originalsourceid><addsrcrecordid>eNqNkU9vEzEQxS0EomnhEyChlbgglU3H9tq75hYtf6WiHijnlWNPGkcbu9jeoH57HBIixAFxskf-vfGbeYS8oDCnwOiVNmlu1riNuJuDAWhBPSIzKhjUslPwmMwAQNVMSnFGzlPalFII1j4lZ5xzQUXXzcimX48hOq8z2uprGHfoc3pb3a7RxWphd9pnfYfpTfXOJf1Hqb2tFmPGWJRuh6lyvrqJd9o78-vtC1pnStux6otFl3J8eEaerPSY8PnxvCDfPry_7T_V1zcfP_eL61o3tMs1is5wxZVUICTiUlsjoAFsNLUKm463AGgN1Y0wtrPK2FZYJplmwshy5xfk9aHvfQzfJ0x5KP8bHEftMUxpYE3LG2iEaAr66i90E6Yy0rinFONlR5wVih8oE0NKEVfDfXRbHR8GCsM-iqFEMRyjGI5RFNXLY-9puUV70vzefQEuD8APXIZVMg69wRNWwpJUSS4U7GMsdPf_dO9yiSX4Pkw-F-nVQbq3eRrwX95_Av4puH4</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2492315832</pqid></control><display><type>article</type><title>Chlorinated Solvents: Their Advantages, Disadvantages, and Alternatives in Organic and Medicinal Chemistry</title><source>ACS Publications</source><source>Web of Science - Science Citation Index Expanded - 2021&lt;img src="https://exlibris-pub.s3.amazonaws.com/fromwos-v2.jpg" /&gt;</source><creator>Jordan, Andrew ; Stoy, Patrick ; Sneddon, Helen F</creator><creatorcontrib>Jordan, Andrew ; Stoy, Patrick ; Sneddon, Helen F</creatorcontrib><description>Chlorinated solvents were once, and in many places are still, ubiquitous in chemistry laboratories. This review explores the properties that led to such widespread use, why there is now an increasing drive to minimize usage, and what alternatives are currently available.</description><identifier>ISSN: 0009-2665</identifier><identifier>EISSN: 1520-6890</identifier><identifier>DOI: 10.1021/acs.chemrev.0c00709</identifier><identifier>PMID: 33351588</identifier><language>eng</language><publisher>WASHINGTON: American Chemical Society</publisher><subject>Chemistry ; Chemistry, Multidisciplinary ; Physical Sciences ; Science &amp; Technology ; Solvents</subject><ispartof>Chemical reviews, 2021-02, Vol.121 (3), p.1582-1622</ispartof><rights>2020 American Chemical Society</rights><rights>Copyright American Chemical Society Feb 10, 2021</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>true</woscitedreferencessubscribed><woscitedreferencescount>76</woscitedreferencescount><woscitedreferencesoriginalsourcerecordid>wos000619635900009</woscitedreferencesoriginalsourcerecordid><citedby>FETCH-LOGICAL-a418t-e58c393969056eebadc5040e4a1d9e483700edc1a45cd8d9cd75d262a25c6d753</citedby><cites>FETCH-LOGICAL-a418t-e58c393969056eebadc5040e4a1d9e483700edc1a45cd8d9cd75d262a25c6d753</cites><orcidid>0000-0002-2964-5043</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://pubs.acs.org/doi/pdf/10.1021/acs.chemrev.0c00709$$EPDF$$P50$$Gacs$$H</linktopdf><linktohtml>$$Uhttps://pubs.acs.org/doi/10.1021/acs.chemrev.0c00709$$EHTML$$P50$$Gacs$$H</linktohtml><link.rule.ids>315,781,785,2766,27081,27929,27930,39263,56743,56793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33351588$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jordan, Andrew</creatorcontrib><creatorcontrib>Stoy, Patrick</creatorcontrib><creatorcontrib>Sneddon, Helen F</creatorcontrib><title>Chlorinated Solvents: Their Advantages, Disadvantages, and Alternatives in Organic and Medicinal Chemistry</title><title>Chemical reviews</title><addtitle>CHEM REV</addtitle><addtitle>Chem. Rev</addtitle><description>Chlorinated solvents were once, and in many places are still, ubiquitous in chemistry laboratories. This review explores the properties that led to such widespread use, why there is now an increasing drive to minimize usage, and what alternatives are currently available.</description><subject>Chemistry</subject><subject>Chemistry, Multidisciplinary</subject><subject>Physical Sciences</subject><subject>Science &amp; Technology</subject><subject>Solvents</subject><issn>0009-2665</issn><issn>1520-6890</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>HGBXW</sourceid><recordid>eNqNkU9vEzEQxS0EomnhEyChlbgglU3H9tq75hYtf6WiHijnlWNPGkcbu9jeoH57HBIixAFxskf-vfGbeYS8oDCnwOiVNmlu1riNuJuDAWhBPSIzKhjUslPwmMwAQNVMSnFGzlPalFII1j4lZ5xzQUXXzcimX48hOq8z2uprGHfoc3pb3a7RxWphd9pnfYfpTfXOJf1Hqb2tFmPGWJRuh6lyvrqJd9o78-vtC1pnStux6otFl3J8eEaerPSY8PnxvCDfPry_7T_V1zcfP_eL61o3tMs1is5wxZVUICTiUlsjoAFsNLUKm463AGgN1Y0wtrPK2FZYJplmwshy5xfk9aHvfQzfJ0x5KP8bHEftMUxpYE3LG2iEaAr66i90E6Yy0rinFONlR5wVih8oE0NKEVfDfXRbHR8GCsM-iqFEMRyjGI5RFNXLY-9puUV70vzefQEuD8APXIZVMg69wRNWwpJUSS4U7GMsdPf_dO9yiSX4Pkw-F-nVQbq3eRrwX95_Av4puH4</recordid><startdate>20210210</startdate><enddate>20210210</enddate><creator>Jordan, Andrew</creator><creator>Stoy, Patrick</creator><creator>Sneddon, Helen F</creator><general>American Chemical Society</general><general>Amer Chemical Soc</general><scope>BLEPL</scope><scope>DTL</scope><scope>HGBXW</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7SR</scope><scope>8BQ</scope><scope>8FD</scope><scope>JG9</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-2964-5043</orcidid></search><sort><creationdate>20210210</creationdate><title>Chlorinated Solvents: Their Advantages, Disadvantages, and Alternatives in Organic and Medicinal Chemistry</title><author>Jordan, Andrew ; Stoy, Patrick ; Sneddon, Helen F</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a418t-e58c393969056eebadc5040e4a1d9e483700edc1a45cd8d9cd75d262a25c6d753</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Chemistry</topic><topic>Chemistry, Multidisciplinary</topic><topic>Physical Sciences</topic><topic>Science &amp; Technology</topic><topic>Solvents</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jordan, Andrew</creatorcontrib><creatorcontrib>Stoy, Patrick</creatorcontrib><creatorcontrib>Sneddon, Helen F</creatorcontrib><collection>Web of Science Core Collection</collection><collection>Science Citation Index Expanded</collection><collection>Web of Science - Science Citation Index Expanded - 2021</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Engineered Materials Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Materials Research Database</collection><collection>MEDLINE - Academic</collection><jtitle>Chemical reviews</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jordan, Andrew</au><au>Stoy, Patrick</au><au>Sneddon, Helen F</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Chlorinated Solvents: Their Advantages, Disadvantages, and Alternatives in Organic and Medicinal Chemistry</atitle><jtitle>Chemical reviews</jtitle><stitle>CHEM REV</stitle><addtitle>Chem. Rev</addtitle><date>2021-02-10</date><risdate>2021</risdate><volume>121</volume><issue>3</issue><spage>1582</spage><epage>1622</epage><pages>1582-1622</pages><issn>0009-2665</issn><eissn>1520-6890</eissn><abstract>Chlorinated solvents were once, and in many places are still, ubiquitous in chemistry laboratories. This review explores the properties that led to such widespread use, why there is now an increasing drive to minimize usage, and what alternatives are currently available.</abstract><cop>WASHINGTON</cop><pub>American Chemical Society</pub><pmid>33351588</pmid><doi>10.1021/acs.chemrev.0c00709</doi><tpages>41</tpages><orcidid>https://orcid.org/0000-0002-2964-5043</orcidid><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0009-2665
ispartof Chemical reviews, 2021-02, Vol.121 (3), p.1582-1622
issn 0009-2665
1520-6890
language eng
recordid cdi_pubmed_primary_33351588
source ACS Publications; Web of Science - Science Citation Index Expanded - 2021<img src="https://exlibris-pub.s3.amazonaws.com/fromwos-v2.jpg" />
subjects Chemistry
Chemistry, Multidisciplinary
Physical Sciences
Science & Technology
Solvents
title Chlorinated Solvents: Their Advantages, Disadvantages, and Alternatives in Organic and Medicinal Chemistry
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-15T10%3A47%3A01IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Chlorinated%20Solvents:%20Their%20Advantages,%20Disadvantages,%20and%20Alternatives%20in%20Organic%20and%20Medicinal%20Chemistry&rft.jtitle=Chemical%20reviews&rft.au=Jordan,%20Andrew&rft.date=2021-02-10&rft.volume=121&rft.issue=3&rft.spage=1582&rft.epage=1622&rft.pages=1582-1622&rft.issn=0009-2665&rft.eissn=1520-6890&rft_id=info:doi/10.1021/acs.chemrev.0c00709&rft_dat=%3Cproquest_pubme%3E2492315832%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2492315832&rft_id=info:pmid/33351588&rfr_iscdi=true