Chlorinated Solvents: Their Advantages, Disadvantages, and Alternatives in Organic and Medicinal Chemistry

Chlorinated solvents were once, and in many places are still, ubiquitous in chemistry laboratories. This review explores the properties that led to such widespread use, why there is now an increasing drive to minimize usage, and what alternatives are currently available.

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Veröffentlicht in:Chemical reviews 2021-02, Vol.121 (3), p.1582-1622
Hauptverfasser: Jordan, Andrew, Stoy, Patrick, Sneddon, Helen F
Format: Artikel
Sprache:eng
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Zusammenfassung:Chlorinated solvents were once, and in many places are still, ubiquitous in chemistry laboratories. This review explores the properties that led to such widespread use, why there is now an increasing drive to minimize usage, and what alternatives are currently available.
ISSN:0009-2665
1520-6890
DOI:10.1021/acs.chemrev.0c00709