Aromatic Ring Substituted Aaptamine Analogues as Potential Cytotoxic Agents against Extranodal Natural Killer/T-Cell Lymphoma

A chemical modification study was conducted on the marine natural product aaptamine (1), isolated from the marine sponge Aaptos aaptos. Thirty new derivatives substituted by various aromatic rings at the 3- and 7-positions of aaptamine were prepared by bromination, followed by the Suzuki coupling re...

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Veröffentlicht in:Journal of natural products (Washington, D.C.) D.C.), 2020-12, Vol.83 (12), p.3758-3763
Hauptverfasser: Yang, Fan, Gao, Yuan, Chang, Yung-Ting, Zou, Yike, Houk, K. N, Lu, Jing-Rong, He, Jing, Tang, Wei-Zhuo, Liao, Hong-Ze, Han, Hua, Lin, Hou-Wen
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Sprache:eng
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