Mayo Normative Studies: Regression-Based Normative Data for the Auditory Verbal Learning Test for Ages 30–91 Years and the Importance of Adjusting for Sex

Objective: Rey's Auditory Verbal Learning Test (AVLT) is a widely used word list memory test. We update normative data to include adjustment for verbal memory performance differences between men and women and illustrate the effect of this sex adjustment and the importance of excluding participa...

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Veröffentlicht in:Journal of the International Neuropsychological Society 2021-03, Vol.27 (3), p.211-226, Article 1355617720000752
Hauptverfasser: Stricker, Nikki H., Christianson, Teresa J., Lundt, Emily S., Alden, Eva C., Machulda, Mary M., Fields, Julie A., Kremers, Walter K., Jack, Clifford R., Knopman, David S., Mielke, Michelle M., Petersen, Ronald C.
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Sprache:eng
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Zusammenfassung:Objective: Rey's Auditory Verbal Learning Test (AVLT) is a widely used word list memory test. We update normative data to include adjustment for verbal memory performance differences between men and women and illustrate the effect of this sex adjustment and the importance of excluding participants with mild cognitive impairment (MCI) from normative samples. Method: This study advances the Mayo's Older Americans Normative Studies (MOANS) by using a new population-based sample through the Mayo Clinic Study of Aging, which randomly samples residents of Olmsted County, Minnesota, from age- and sex-stratified groups. Regression-based normative T-score formulas were derived from 4428 cognitively unimpaired adults aged 30-91 years. Fully adjusted T-scores correct for age, sex, and education. We also derived T-scores that correct for (1) age or (2) age and sex. Test-retest reliability data are provided. Results: From raw score analyses, sex explained a significant amount of variance in performance above and beyond age (8-10%). Applying original age-adjusted MOANS norms to the current sample resulted in significantly fewer-than-expected participants with low delayed recall performance, particularly in women. After application of new T-scores adjusted only for age, even in normative data derived from this sample, these age-adjusted T-scores showed scores Conclusions: Our findings highlight the importance of using normative data that adjust for sex with measures of verbal memory and provide new normative data that allow for this adjustment for the AVLT.
ISSN:1355-6177
1469-7661
DOI:10.1017/S1355617720000752