Theranostic application of nanoemulsion in chemotherapy

Teaser: The attractive multifunctionality platform of nanoemulsion has presented smart theranostic role with promising antitumor efficacy and multimodal diagnostic functionalities. Novel targeting nanoemulsion strategy can sense the target to ferry cargo specifically in the cancer microenvironment. Theranostic approach grasps the potential to revolutionize the diagnosis, treatment, and prognosis in cancer, where the novel drug delivery systems hold the possibilities of detecting the disease at an early stage with the instantaneous treatment. Many preclinical approaches of nanoemulsion with entrapped contrast and chemotherapeutic agents documented to act specifically to the tumor microenvironment for diagnosis and therapeutic purposes. However, bringing these theranostic nanoemulsions through preclinical outcomes to the bedside of patients has to cross several fundamental hurdles, including in vivo behavior of the delivery tool, degradation, and clearance from the system, long-term toxicities, etc. Here, in this article, we discussed the recent advancement of nanoemulsion application in the molecular imaging with simultaneous therapeutic efficacy in a single delivery system.