Development of bioconjugated dye-doped poly(styrene-co-maleimide) nanoparticles as a new bioprobe

Development of bioconjugated dye-doped poly(styrene-co-maleimide) nanoparticles as a new bioprobe

Fluorescent dye-doped poly(styrene- co -maleimide) nanoparticles were synthesised and functionalized with amine groups and avidin and the dye-loading was varied. The nanoparticles showed great potential as bioprobes when conjugated with biotinylated antibodies. Fluorescent dye-doped poly(styrene- co...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of materials chemistry. B, Materials for biology and medicine Materials for biology and medicine, 2015-04, Vol.3 (13), p.2635-264
Hauptverfasser: Swanepoel, A, du Preez, I, Mahlangu, T, Chetty, A, Klumperman, B
Format: Artikel
Sprache:eng
Schlagworte:
Amines
Antibodies
Biology
Dyes
Medicine
Nanoparticles
Polystyrene resins
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Fluorescent dye-doped poly(styrene- co -maleimide) nanoparticles were synthesised and functionalized with amine groups and avidin and the dye-loading was varied. The nanoparticles showed great potential as bioprobes when conjugated with biotinylated antibodies. Fluorescent dye-doped poly(styrene- co -maleimide) nanoparticles were synthesised and functionalized with amine groups and avidin and the dye-loading was varied.
ISSN:2050-750X
2050-7518
DOI:10.1039/c4tb01520g