Cucurbit[7]uril-functionalized magnetic nanoparticles for imaging-guided cancer therapy

Herein we developed cucurbit[7]uril covalently modified Fe 3 O 4 nanoparticles for facile surface modification via host-guest interactions to realize targeted drug delivery and magnetic resonance imaging of tumors in vivo . Cucurbit[7]uril-anchored Fe 3 O 4 nanoparticles allowed facile surface funct...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of materials chemistry. B, Materials for biology and medicine Materials for biology and medicine, 2020-04, Vol.8 (14), p.2749-2753
Hauptverfasser:	Yue, Ludan, Sun, Chen, Kwong, Cheryl H. T, Wang, Ruibing
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bridged-Ring Compounds - chemistry Cancer therapies Drug delivery Drug Delivery Systems Flow cytometry Fluorescence Humans Imidazoles - chemistry Iron oxides Magnetic Resonance Imaging Magnetite Nanoparticles - chemistry Medical imaging Nanoparticles Neoplasms - diagnostic imaging Neoplasms - drug therapy NMR Nuclear magnetic resonance Particle Size Surface Properties Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Herein we developed cucurbit[7]uril covalently modified Fe 3 O 4 nanoparticles for facile surface modification via host-guest interactions to realize targeted drug delivery and magnetic resonance imaging of tumors in vivo . Cucurbit[7]uril-anchored Fe 3 O 4 nanoparticles allowed facile surface functionalization and MRI-guided targeted drug delivery for cancer therapy.
ISSN:	2050-750X 2050-7518
DOI:	10.1039/d0tb00306a