Neurogenesis right under your nose

Neurogenesis right under your nose

Postmortem studies have previously suggested that adult olfactory neurogenesis occurs in humans. In new research, Durante and colleagues obtained fresh tissue from healthy adult humans via endoscopic nasal surgery and used single-cell RNA sequencing (RNA-seq) to identify the entire neurogenic trajec...

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Veröffentlicht in:Nature neuroscience 2020-03, Vol.23 (3), p.297-298
Hauptverfasser: Berger, Thomas, Lee, Hyunah, Thuret, Sandrine
Format: Artikel
Sprache:eng
Schlagworte:
631/378/2624/1703
631/378/368/2431
Animal Genetics and Genomics
Behavioral Sciences
Biological Techniques
Biomedical and Life Sciences
Biomedicine
Cell Differentiation
Epithelium
Forecasts and trends
Gene sequencing
Genetic research
Humans
Life Sciences & Biomedicine
Neurobiology
Neurogenesis
Neurological research
Neurosciences
Neurosciences & Neurology
News & Views
news-and-views
Nose
Olfactory cortex
Olfactory epithelium
Ribonucleic acid
RNA
Science & Technology
Single-Cell Analysis
Smell
Surgery
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Zusammenfassung:Postmortem studies have previously suggested that adult olfactory neurogenesis occurs in humans. In new research, Durante and colleagues obtained fresh tissue from healthy adult humans via endoscopic nasal surgery and used single-cell RNA sequencing (RNA-seq) to identify the entire neurogenic trajectory in the olfactory epithelium, confirming the existence of human olfactory neurogenesis.
ISSN:1097-6256
1546-1726
DOI:10.1038/s41593-020-0596-8