Biomedical applications of laminarin

[Display omitted] •Review of key properties of laminarin.•Analysis of chemical modification strategies of this polysaccharide.•Discussion on its emerging applications in biomedicine. The ocean is par excellence a fertile territory of biodiversity on our planet. Marine-derived polysaccharides have be...

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Veröffentlicht in:Carbohydrate polymers 2020-03, Vol.232, p.115774-115774, Article 115774
Hauptverfasser: Zargarzadeh, Mehrzad, Amaral, Adérito J.R., Custódio, Catarina A., Mano, João F.
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Sprache:eng
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Zusammenfassung:[Display omitted] •Review of key properties of laminarin.•Analysis of chemical modification strategies of this polysaccharide.•Discussion on its emerging applications in biomedicine. The ocean is par excellence a fertile territory of biodiversity on our planet. Marine-derived polysaccharides have been applied as functional materials in biomedicine due to their attractive bioactive properties, safety, high availability and low-cost production. Laminarin (or laminaran), a low molecular weight β-glucan storage polysaccharide present in brown algae, can be (bio-) chemically modified to enhance its biological activity and employed in cancer therapies, drug/gene delivery, tissue engineering, antioxidant and anti-inflammatory functions. This review provides a brief overview on laminarin characteristics, modification strategies and highlights its pivotal biomedical applications.
ISSN:0144-8617
1879-1344
DOI:10.1016/j.carbpol.2019.115774