Peptide-based short single β-strand mimics without hydrogen bonding or aggregation

Generation of short peptides with a single β-strand structure in solution is difficult. Herein, we design a new class of single β-strand peptidic mimics that are stable without self-aggregation in protic and non-protic solvents. Introduction of one present β-strand mimic can induce and propagate the...

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Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2020-02, Vol.56 (1), p.1573-1576
Hauptverfasser:	Zhai, Luhan, Otani, Yuko, Hori, Yukiko, Tomita, Taisuke, Ohwada, Tomohiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Agglomeration Hydrogen Bonding Magnetic Resonance Spectroscopy Molecular Dynamics Simulation NMR Nuclear magnetic resonance Peptides Peptides - chemistry Protein Conformation, beta-Strand Temperature
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