Cell therapy in muscular disorders: the future lies in comparisons of progenitors

Cell therapy approaches dedicated to the treatment of dystrophinopathies and involving essentially myoblasts and mesoangioblasts have produced mitigated clinical results. If several types of alternative progenitors have been developed, no standardized comparison has been carried out yet to investiga...

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Veröffentlicht in:M.S. Médecine sciences 2019-11, Vol.35 Hors série n° 2, p.7
Hauptverfasser: Vilquin, Jean-Thomas, Braun, Serge
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container_title M.S. Médecine sciences
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creator Vilquin, Jean-Thomas
Braun, Serge
description Cell therapy approaches dedicated to the treatment of dystrophinopathies and involving essentially myoblasts and mesoangioblasts have produced mitigated clinical results. If several types of alternative progenitors have been developed, no standardized comparison has been carried out yet to investigate their regenerative efficacy in vivo, at least at a local level. A comparative study has therefore been designed recently aiming at giving a new impetus to this therapeutic field.
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subjects Animals
Cell Differentiation
Cell- and Tissue-Based Therapy - methods
Cell- and Tissue-Based Therapy - trends
Cells, Cultured
Humans
Muscle, Skeletal - cytology
Muscle, Skeletal - physiology
Muscular Diseases - therapy
Myoblasts - physiology
Physiology, Comparative - methods
Physiology, Comparative - standards
Physiology, Comparative - trends
Reference Standards
Regenerative Medicine - standards
Regenerative Medicine - trends
Stem Cells - classification
Stem Cells - cytology
Stem Cells - physiology
title Cell therapy in muscular disorders: the future lies in comparisons of progenitors
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