Aggregation-induced emission-active Au nanoclusters for ratiometric sensing and bioimaging of highly reactive oxygen species
We prepared a nanoprobe through self-assembly of gold nanoclusters (AuNCs) and using FITC-modified hyaluronic acid (HA) for ratiometric sensing of highly reactive oxygen species (hROS). Taking advantage of the aggregation-induced emission (AIE) properties of the self-assembled AuNCs, hROS-responsive...
Gespeichert in:
| Veröffentlicht in: | Chemical communications (Cambridge, England) England), 2019-12, Vol.55 (1), p.1597-151 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 151 |
|---|---|
| container_issue | 1 |
| container_start_page | 1597 |
| container_title | Chemical communications (Cambridge, England) |
| container_volume | 55 |
| creator | Ran, Xiang Wang, Zhenzhen Pu, Fang Liu, Zhen Ren, Jinsong Qu, Xiaogang |
| description | We prepared a nanoprobe through self-assembly of gold nanoclusters (AuNCs) and using FITC-modified hyaluronic acid (HA) for ratiometric sensing of highly reactive oxygen species (hROS). Taking advantage of the aggregation-induced emission (AIE) properties of the self-assembled AuNCs, hROS-responsive cleavage of HA, and the ratiometric signal change of dual-emission, the nanoprobe exhibited excellent performance in imaging hROS in living cells.
A nanoprobe based on aggregation-induced emission-active Au nanoclusters for ratiometric sensing and bioimaging of highly reactive oxygen species is constructed. |
| doi_str_mv | 10.1039/c9cc08170d |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmed_primary_31782429</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2320376445</sourcerecordid><originalsourceid>FETCH-LOGICAL-c378t-ba693dac50826056de82ba83e3f0972f6c56e83c0c2d1bc656f98d9d774c004d3</originalsourceid><addsrcrecordid>eNpdkc2L1TAUxYMozji6ca8E3IhQTZqPJstH_YQBNwruSnpz28nQlzyTVnzgH2_re45gNje595fDPRxCnnL2mjNh34AFYIY3zN8jl1xoWSlpvt3f7spWjZDqgjwq5ZathyvzkFwI3pha1vaS_NqNY8bRzSHFKkS_AHqK-1DK1nAwhx9IdwuNLiaYljJjLnRImebtyx7nHIAWjCXEkbroaR9S2Ltxe6aB3oTxZjrSjGel9PM4YqTlgBCwPCYPBjcVfHKuV-Tr-3df2o_V9ecPn9rddQWiMXPVO22Fd6CYqTVT2qOpe2cEioHZph40KI1GAIPa8x600oM13vqmkcCY9OKKvDzpHnL6vmCZu9Ug4DS5iGkpXS1qJhotpVrRF_-ht2nJcd1uo6TRRnG5Uq9OFORUSsahO-TVdT52nHVbJl1r2_ZPJm9X-PlZcun36O_QvyGswLMTkAvcTf-FKn4DHdOSqg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2324868514</pqid></control><display><type>article</type><title>Aggregation-induced emission-active Au nanoclusters for ratiometric sensing and bioimaging of highly reactive oxygen species</title><source>MEDLINE</source><source>Royal Society Of Chemistry Journals</source><source>Alma/SFX Local Collection</source><creator>Ran, Xiang ; Wang, Zhenzhen ; Pu, Fang ; Liu, Zhen ; Ren, Jinsong ; Qu, Xiaogang</creator><creatorcontrib>Ran, Xiang ; Wang, Zhenzhen ; Pu, Fang ; Liu, Zhen ; Ren, Jinsong ; Qu, Xiaogang</creatorcontrib><description>We prepared a nanoprobe through self-assembly of gold nanoclusters (AuNCs) and using FITC-modified hyaluronic acid (HA) for ratiometric sensing of highly reactive oxygen species (hROS). Taking advantage of the aggregation-induced emission (AIE) properties of the self-assembled AuNCs, hROS-responsive cleavage of HA, and the ratiometric signal change of dual-emission, the nanoprobe exhibited excellent performance in imaging hROS in living cells.
A nanoprobe based on aggregation-induced emission-active Au nanoclusters for ratiometric sensing and bioimaging of highly reactive oxygen species is constructed.</description><identifier>ISSN: 1359-7345</identifier><identifier>EISSN: 1364-548X</identifier><identifier>DOI: 10.1039/c9cc08170d</identifier><identifier>PMID: 31782429</identifier><language>eng</language><publisher>England: Royal Society of Chemistry</publisher><subject>Agglomeration ; Animals ; Emission ; Glutathione - chemistry ; Gold - chemistry ; Hyaluronic acid ; Lipopolysaccharides - pharmacology ; Macrophages - cytology ; Macrophages - enzymology ; Macrophages - metabolism ; Medical imaging ; Metal Nanoparticles - chemistry ; Metal Nanoparticles - toxicity ; Mice ; Microscopy, Fluorescence ; Nanoclusters ; RAW 264.7 Cells ; Reactive Oxygen Species - analysis ; Self-assembly ; Spectrometry, Fluorescence - methods</subject><ispartof>Chemical communications (Cambridge, England), 2019-12, Vol.55 (1), p.1597-151</ispartof><rights>Copyright Royal Society of Chemistry 2019</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c378t-ba693dac50826056de82ba83e3f0972f6c56e83c0c2d1bc656f98d9d774c004d3</citedby><cites>FETCH-LOGICAL-c378t-ba693dac50826056de82ba83e3f0972f6c56e83c0c2d1bc656f98d9d774c004d3</cites><orcidid>0000-0002-7506-627X ; 0000-0003-2868-3205</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31782429$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ran, Xiang</creatorcontrib><creatorcontrib>Wang, Zhenzhen</creatorcontrib><creatorcontrib>Pu, Fang</creatorcontrib><creatorcontrib>Liu, Zhen</creatorcontrib><creatorcontrib>Ren, Jinsong</creatorcontrib><creatorcontrib>Qu, Xiaogang</creatorcontrib><title>Aggregation-induced emission-active Au nanoclusters for ratiometric sensing and bioimaging of highly reactive oxygen species</title><title>Chemical communications (Cambridge, England)</title><addtitle>Chem Commun (Camb)</addtitle><description>We prepared a nanoprobe through self-assembly of gold nanoclusters (AuNCs) and using FITC-modified hyaluronic acid (HA) for ratiometric sensing of highly reactive oxygen species (hROS). Taking advantage of the aggregation-induced emission (AIE) properties of the self-assembled AuNCs, hROS-responsive cleavage of HA, and the ratiometric signal change of dual-emission, the nanoprobe exhibited excellent performance in imaging hROS in living cells.
A nanoprobe based on aggregation-induced emission-active Au nanoclusters for ratiometric sensing and bioimaging of highly reactive oxygen species is constructed.</description><subject>Agglomeration</subject><subject>Animals</subject><subject>Emission</subject><subject>Glutathione - chemistry</subject><subject>Gold - chemistry</subject><subject>Hyaluronic acid</subject><subject>Lipopolysaccharides - pharmacology</subject><subject>Macrophages - cytology</subject><subject>Macrophages - enzymology</subject><subject>Macrophages - metabolism</subject><subject>Medical imaging</subject><subject>Metal Nanoparticles - chemistry</subject><subject>Metal Nanoparticles - toxicity</subject><subject>Mice</subject><subject>Microscopy, Fluorescence</subject><subject>Nanoclusters</subject><subject>RAW 264.7 Cells</subject><subject>Reactive Oxygen Species - analysis</subject><subject>Self-assembly</subject><subject>Spectrometry, Fluorescence - methods</subject><issn>1359-7345</issn><issn>1364-548X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkc2L1TAUxYMozji6ca8E3IhQTZqPJstH_YQBNwruSnpz28nQlzyTVnzgH2_re45gNje595fDPRxCnnL2mjNh34AFYIY3zN8jl1xoWSlpvt3f7spWjZDqgjwq5ZathyvzkFwI3pha1vaS_NqNY8bRzSHFKkS_AHqK-1DK1nAwhx9IdwuNLiaYljJjLnRImebtyx7nHIAWjCXEkbroaR9S2Ltxe6aB3oTxZjrSjGel9PM4YqTlgBCwPCYPBjcVfHKuV-Tr-3df2o_V9ecPn9rddQWiMXPVO22Fd6CYqTVT2qOpe2cEioHZph40KI1GAIPa8x600oM13vqmkcCY9OKKvDzpHnL6vmCZu9Ug4DS5iGkpXS1qJhotpVrRF_-ht2nJcd1uo6TRRnG5Uq9OFORUSsahO-TVdT52nHVbJl1r2_ZPJm9X-PlZcun36O_QvyGswLMTkAvcTf-FKn4DHdOSqg</recordid><startdate>20191228</startdate><enddate>20191228</enddate><creator>Ran, Xiang</creator><creator>Wang, Zhenzhen</creator><creator>Pu, Fang</creator><creator>Liu, Zhen</creator><creator>Ren, Jinsong</creator><creator>Qu, Xiaogang</creator><general>Royal Society of Chemistry</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7SR</scope><scope>7U5</scope><scope>8BQ</scope><scope>8FD</scope><scope>JG9</scope><scope>L7M</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-7506-627X</orcidid><orcidid>https://orcid.org/0000-0003-2868-3205</orcidid></search><sort><creationdate>20191228</creationdate><title>Aggregation-induced emission-active Au nanoclusters for ratiometric sensing and bioimaging of highly reactive oxygen species</title><author>Ran, Xiang ; Wang, Zhenzhen ; Pu, Fang ; Liu, Zhen ; Ren, Jinsong ; Qu, Xiaogang</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c378t-ba693dac50826056de82ba83e3f0972f6c56e83c0c2d1bc656f98d9d774c004d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Agglomeration</topic><topic>Animals</topic><topic>Emission</topic><topic>Glutathione - chemistry</topic><topic>Gold - chemistry</topic><topic>Hyaluronic acid</topic><topic>Lipopolysaccharides - pharmacology</topic><topic>Macrophages - cytology</topic><topic>Macrophages - enzymology</topic><topic>Macrophages - metabolism</topic><topic>Medical imaging</topic><topic>Metal Nanoparticles - chemistry</topic><topic>Metal Nanoparticles - toxicity</topic><topic>Mice</topic><topic>Microscopy, Fluorescence</topic><topic>Nanoclusters</topic><topic>RAW 264.7 Cells</topic><topic>Reactive Oxygen Species - analysis</topic><topic>Self-assembly</topic><topic>Spectrometry, Fluorescence - methods</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ran, Xiang</creatorcontrib><creatorcontrib>Wang, Zhenzhen</creatorcontrib><creatorcontrib>Pu, Fang</creatorcontrib><creatorcontrib>Liu, Zhen</creatorcontrib><creatorcontrib>Ren, Jinsong</creatorcontrib><creatorcontrib>Qu, Xiaogang</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Engineered Materials Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Materials Research Database</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>MEDLINE - Academic</collection><jtitle>Chemical communications (Cambridge, England)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ran, Xiang</au><au>Wang, Zhenzhen</au><au>Pu, Fang</au><au>Liu, Zhen</au><au>Ren, Jinsong</au><au>Qu, Xiaogang</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Aggregation-induced emission-active Au nanoclusters for ratiometric sensing and bioimaging of highly reactive oxygen species</atitle><jtitle>Chemical communications (Cambridge, England)</jtitle><addtitle>Chem Commun (Camb)</addtitle><date>2019-12-28</date><risdate>2019</risdate><volume>55</volume><issue>1</issue><spage>1597</spage><epage>151</epage><pages>1597-151</pages><issn>1359-7345</issn><eissn>1364-548X</eissn><abstract>We prepared a nanoprobe through self-assembly of gold nanoclusters (AuNCs) and using FITC-modified hyaluronic acid (HA) for ratiometric sensing of highly reactive oxygen species (hROS). Taking advantage of the aggregation-induced emission (AIE) properties of the self-assembled AuNCs, hROS-responsive cleavage of HA, and the ratiometric signal change of dual-emission, the nanoprobe exhibited excellent performance in imaging hROS in living cells.
A nanoprobe based on aggregation-induced emission-active Au nanoclusters for ratiometric sensing and bioimaging of highly reactive oxygen species is constructed.</abstract><cop>England</cop><pub>Royal Society of Chemistry</pub><pmid>31782429</pmid><doi>10.1039/c9cc08170d</doi><tpages>4</tpages><orcidid>https://orcid.org/0000-0002-7506-627X</orcidid><orcidid>https://orcid.org/0000-0003-2868-3205</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1359-7345 |
| ispartof | Chemical communications (Cambridge, England), 2019-12, Vol.55 (1), p.1597-151 |
| issn | 1359-7345 1364-548X |
| language | eng |
| recordid | cdi_pubmed_primary_31782429 |
| source | MEDLINE; Royal Society Of Chemistry Journals; Alma/SFX Local Collection |
| subjects | Agglomeration Animals Emission Glutathione - chemistry Gold - chemistry Hyaluronic acid Lipopolysaccharides - pharmacology Macrophages - cytology Macrophages - enzymology Macrophages - metabolism Medical imaging Metal Nanoparticles - chemistry Metal Nanoparticles - toxicity Mice Microscopy, Fluorescence Nanoclusters RAW 264.7 Cells Reactive Oxygen Species - analysis Self-assembly Spectrometry, Fluorescence - methods |
| title | Aggregation-induced emission-active Au nanoclusters for ratiometric sensing and bioimaging of highly reactive oxygen species |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-29T16%3A32%3A43IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Aggregation-induced%20emission-active%20Au%20nanoclusters%20for%20ratiometric%20sensing%20and%20bioimaging%20of%20highly%20reactive%20oxygen%20species&rft.jtitle=Chemical%20communications%20(Cambridge,%20England)&rft.au=Ran,%20Xiang&rft.date=2019-12-28&rft.volume=55&rft.issue=1&rft.spage=1597&rft.epage=151&rft.pages=1597-151&rft.issn=1359-7345&rft.eissn=1364-548X&rft_id=info:doi/10.1039/c9cc08170d&rft_dat=%3Cproquest_pubme%3E2320376445%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2324868514&rft_id=info:pmid/31782429&rfr_iscdi=true |