Combinatorial Oxytocin Neuropharmacology in Social Cognition
The efficacy and reliability of using intranasal oxytocin (OT) to clinically enhance social functions remains undependable. We discuss the potential benefit of concurrent administration of OT and naloxone (NAL) to robustly modulate social behavior. We further suggest that combinatorial neuropharmaco...
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Veröffentlicht in: | Trends in cognitive sciences 2020-01, Vol.24 (1), p.8-12 |
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creator | Fan, Siqi Weinberg-Wolf, Hannah Piva, Matthew Dal Monte, Olga Chang, Steve W.C. |
description | The efficacy and reliability of using intranasal oxytocin (OT) to clinically enhance social functions remains undependable. We discuss the potential benefit of concurrent administration of OT and naloxone (NAL) to robustly modulate social behavior. We further suggest that combinatorial neuropharmacology approaches should exploit the interactions between OT and serotonin to regulate social functions. |
doi_str_mv | 10.1016/j.tics.2019.10.004 |
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We discuss the potential benefit of concurrent administration of OT and naloxone (NAL) to robustly modulate social behavior. We further suggest that combinatorial neuropharmacology approaches should exploit the interactions between OT and serotonin to regulate social functions.</description><identifier>ISSN: 1364-6613</identifier><identifier>EISSN: 1879-307X</identifier><identifier>DOI: 10.1016/j.tics.2019.10.004</identifier><identifier>PMID: 31735541</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Autism Spectrum Disorder - therapy ; autism spectrum disorders ; combinatorial neuropharmacology ; Humans ; naloxone ; Neuropharmacology ; oxytocin ; Oxytocin - administration & dosage ; Oxytocin - therapeutic use ; Reproducibility of Results ; serotonin ; Social Behavior ; Social Cognition</subject><ispartof>Trends in cognitive sciences, 2020-01, Vol.24 (1), p.8-12</ispartof><rights>2019 Elsevier Ltd</rights><rights>Copyright © 2019 Elsevier Ltd. 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We discuss the potential benefit of concurrent administration of OT and naloxone (NAL) to robustly modulate social behavior. We further suggest that combinatorial neuropharmacology approaches should exploit the interactions between OT and serotonin to regulate social functions.</description><subject>Autism Spectrum Disorder - therapy</subject><subject>autism spectrum disorders</subject><subject>combinatorial neuropharmacology</subject><subject>Humans</subject><subject>naloxone</subject><subject>Neuropharmacology</subject><subject>oxytocin</subject><subject>Oxytocin - administration & dosage</subject><subject>Oxytocin - therapeutic use</subject><subject>Reproducibility of Results</subject><subject>serotonin</subject><subject>Social Behavior</subject><subject>Social Cognition</subject><issn>1364-6613</issn><issn>1879-307X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kD1PwzAURS0EoqXwBxhQR5YEfyROInVBEV9SRQdAYrMc-6W4SuJiJ4j-exy1MDLZuj7v6vkgdElwTDDhN5u4N8rHFJMiBDHGyRGakjwrIoaz9-NwZzyJOCdsgs6832BM0izjp2jCSMbSNCFTtChtW5lO9tYZ2cxX37veKtPNn2FwdvshXSuVbex6Nw_hS3gKUGnXnemN7c7RSS0bDxeHc4be7u9ey8douXp4Km-XkUoo7SOeq4LWmgJoRknBqzrTusgqJpWuVF5RzsNCPMeYMq2rjKs8hQTylAJhElI2Q9f73q2znwP4XrTGK2ga2YEdvKCMpClNcsoDSveoctZ7B7XYOtNKtxMEi9Ga2IjRmhitjVmwFoauDv1D1YL-G_nVFIDFHoDwyy8DTnhloFOgjQPVC23Nf_0_Jf5-aw</recordid><startdate>202001</startdate><enddate>202001</enddate><creator>Fan, Siqi</creator><creator>Weinberg-Wolf, Hannah</creator><creator>Piva, Matthew</creator><creator>Dal Monte, Olga</creator><creator>Chang, Steve W.C.</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>202001</creationdate><title>Combinatorial Oxytocin Neuropharmacology in Social Cognition</title><author>Fan, Siqi ; Weinberg-Wolf, Hannah ; Piva, Matthew ; Dal Monte, Olga ; Chang, Steve W.C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c422t-68c92fd2eed32196bf7dd97b3acdbc8b266317680023ddb76c85e4e852e13ae53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Autism Spectrum Disorder - therapy</topic><topic>autism spectrum disorders</topic><topic>combinatorial neuropharmacology</topic><topic>Humans</topic><topic>naloxone</topic><topic>Neuropharmacology</topic><topic>oxytocin</topic><topic>Oxytocin - administration & dosage</topic><topic>Oxytocin - therapeutic use</topic><topic>Reproducibility of Results</topic><topic>serotonin</topic><topic>Social Behavior</topic><topic>Social Cognition</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Fan, Siqi</creatorcontrib><creatorcontrib>Weinberg-Wolf, Hannah</creatorcontrib><creatorcontrib>Piva, Matthew</creatorcontrib><creatorcontrib>Dal Monte, Olga</creatorcontrib><creatorcontrib>Chang, Steve W.C.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Trends in cognitive sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Fan, Siqi</au><au>Weinberg-Wolf, Hannah</au><au>Piva, Matthew</au><au>Dal Monte, Olga</au><au>Chang, Steve W.C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Combinatorial Oxytocin Neuropharmacology in Social Cognition</atitle><jtitle>Trends in cognitive sciences</jtitle><addtitle>Trends Cogn Sci</addtitle><date>2020-01</date><risdate>2020</risdate><volume>24</volume><issue>1</issue><spage>8</spage><epage>12</epage><pages>8-12</pages><issn>1364-6613</issn><eissn>1879-307X</eissn><abstract>The efficacy and reliability of using intranasal oxytocin (OT) to clinically enhance social functions remains undependable. 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subjects | Autism Spectrum Disorder - therapy autism spectrum disorders combinatorial neuropharmacology Humans naloxone Neuropharmacology oxytocin Oxytocin - administration & dosage Oxytocin - therapeutic use Reproducibility of Results serotonin Social Behavior Social Cognition |
title | Combinatorial Oxytocin Neuropharmacology in Social Cognition |
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