Combinatorial Oxytocin Neuropharmacology in Social Cognition

The efficacy and reliability of using intranasal oxytocin (OT) to clinically enhance social functions remains undependable. We discuss the potential benefit of concurrent administration of OT and naloxone (NAL) to robustly modulate social behavior. We further suggest that combinatorial neuropharmaco...

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Veröffentlicht in:Trends in cognitive sciences 2020-01, Vol.24 (1), p.8-12
Hauptverfasser: Fan, Siqi, Weinberg-Wolf, Hannah, Piva, Matthew, Dal Monte, Olga, Chang, Steve W.C.
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container_issue 1
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container_title Trends in cognitive sciences
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creator Fan, Siqi
Weinberg-Wolf, Hannah
Piva, Matthew
Dal Monte, Olga
Chang, Steve W.C.
description The efficacy and reliability of using intranasal oxytocin (OT) to clinically enhance social functions remains undependable. We discuss the potential benefit of concurrent administration of OT and naloxone (NAL) to robustly modulate social behavior. We further suggest that combinatorial neuropharmacology approaches should exploit the interactions between OT and serotonin to regulate social functions.
doi_str_mv 10.1016/j.tics.2019.10.004
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subjects Autism Spectrum Disorder - therapy
autism spectrum disorders
combinatorial neuropharmacology
Humans
naloxone
Neuropharmacology
oxytocin
Oxytocin - administration & dosage
Oxytocin - therapeutic use
Reproducibility of Results
serotonin
Social Behavior
Social Cognition
title Combinatorial Oxytocin Neuropharmacology in Social Cognition
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