What Is the Evidence to Support a Correlate of Protection for Measles? A Systematic Review

Abstract Background Many studies assume that the serologic correlate of protection from measles disease is 120 mIU/mL. We systematically reviewed the literature to examine the evidence supporting this correlate of protection. Methods We searched peer-reviewed and gray literature for articles reporti...

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Veröffentlicht in:	The Journal of infectious diseases 2020-04, Vol.221 (10), p.1576-1583
Hauptverfasser:	Bolotin, Shelly, Hughes, Stephanie L, Gul, Nazish, Khan, Sumaiya, Rota, Paul A, Severini, Alberto, Hahné, Susan, Tricco, Andrea, Moss, William J, Orenstein, Walter, Turner, Nikki, Durrheim, David, Heffernan, Jane M, Crowcroft, Natasha
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Antibodies Antibodies, Viral - blood Humans Immunology Infants Infectious Diseases Life Sciences & Biomedicine Measles Measles - prevention & control Measles Vaccine - immunology Microbiology Population studies Science & Technology Serologic Tests
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Zusammenfassung:	Abstract Background Many studies assume that the serologic correlate of protection from measles disease is 120 mIU/mL. We systematically reviewed the literature to examine the evidence supporting this correlate of protection. Methods We searched peer-reviewed and gray literature for articles reporting a measles correlate of protection. We excluded studies focusing on special populations, infants aged
ISSN:	0022-1899 1537-6613
DOI:	10.1093/infdis/jiz380