The impact of infection and inflammation in oncologic 18 F-FDG PET/CT imaging

Sites of infection and inflammation can be misleading in oncology PET/CT imaging because these areas commonly show F-FDG activity. Caution in the interpretation must be taken to avoid the misdiagnosis of malignancy. Utilization of both CT findings as well as patient history can help differentiate be...

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Veröffentlicht in:	Biomedicine & pharmacotherapy 2019-09, Vol.117, p.109168
Hauptverfasser:	Rahman, W Tania, Wale, Daniel J, Viglianti, Benjamin L, Townsend, Danyelle M, Manganaro, Matthew S, Gross, Milton D, Wong, Ka Kit, Rubello, Domenico
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Fluorodeoxyglucose F18 - chemistry Fluorodeoxyglucose F18 - metabolism Humans Infections - diagnostic imaging Inflammation - diagnostic imaging Neoplasms - diagnostic imaging Positron Emission Tomography Computed Tomography
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Zusammenfassung:	Sites of infection and inflammation can be misleading in oncology PET/CT imaging because these areas commonly show F-FDG activity. Caution in the interpretation must be taken to avoid the misdiagnosis of malignancy. Utilization of both CT findings as well as patient history can help differentiate benign infectious and inflammatory processes from malignancy, although occasionally additional work-up may be required. This article discusses the mechanism of F-FDG uptake in infection and inflammation with illustrative examples.
ISSN:	1950-6007