Endocannabinoids and endocannabinoid-like compounds modulate hypoxia-induced permeability in CaCo-2 cells via CB 1 , TRPV1, and PPARα

We have previously reported that endocannabinoids modulate permeability in Caco-2 cells under inflammatory conditions and hypothesised in the present study that endocannabinoids could also modulate permeability in ischemia/reperfusion. Caco-2 cells were grown on cell culture inserts to confluence. T...

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Veröffentlicht in:	Biochemical pharmacology 2019-10, Vol.168, p.465
Hauptverfasser:	Karwad, M A, Couch, D G, Wright, K L, Tufarelli, C, Larvin, M, Lund, J, O'Sullivan, S E
Format:	Artikel
Sprache:	eng
Schlagworte:	Caco-2 Cells Cell Hypoxia - drug effects Cell Hypoxia - physiology Cell Membrane Permeability - drug effects Cell Membrane Permeability - physiology Endocannabinoids - metabolism Endocannabinoids - pharmacology Humans PPAR alpha - metabolism Receptor, Cannabinoid, CB1 - agonists Receptor, Cannabinoid, CB1 - metabolism Transendothelial and Transepithelial Migration - drug effects Transendothelial and Transepithelial Migration - physiology TRPV Cation Channels - metabolism
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