Numerical modeling of ultrasound heating for the correction of viscous heating artifacts in soft tissue temperature measurements
Measuring temperature during focused ultrasound (FUS) procedures is critical for characterization, calibration, and monitoring to ultimately ensure safety and efficacy. Despite the low cost and the high spatial and temporal resolutions of temperature measurements using thermocouples, the viscous hea...
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Veröffentlicht in: | Applied physics letters 2019-05, Vol.114 (20), p.203702-203702 |
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Sprache: | eng |
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Zusammenfassung: | Measuring temperature during focused ultrasound (FUS) procedures is critical for
characterization, calibration, and monitoring to ultimately ensure safety and efficacy.
Despite the low cost and the high spatial and temporal resolutions of temperature
measurements using thermocouples, the viscous heating (VH) artifact at the
thermocouple-tissue interface requires reading corrections for correct thermometric
analysis. In this study, a simulation pipeline is proposed to correct the VH artifact
arising from temperature measurements using thermocouples in FUS fields. The numerical
model consists of simulating a primary source of heating due to ultrasound absorption and
a secondary source of heating from viscous forces generated by the thermocouple in the FUS
field. Our numerical validation found that up to 90% of the measured temperature rise was
due to VH effects. Experimental temperature measurements were performed using
thermocouples embedded in fresh chicken breast samples. Temperature corrections were
demonstrated for single high-intensity FUS pulses at 3.1 MHz and for multiple pulses
(3.1 MHz, 100 Hz, and 500 Hz pulse repetition frequency). The VH accumulated during
sonications and produced a temperature increase of 3.1 °C and 15.3 °C for the single and
multiple pulse sequences, respectively. The methodology presented here enables the
decoupling of the temperature increase generated by absorption and VH. Thus, more reliable
temperature measurements can be extracted from thermocouple measurements by correcting for
VH. |
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ISSN: | 0003-6951 1077-3118 |
DOI: | 10.1063/1.5091108 |