Frustration and Emotional Regulation in Nonsyndromic Craniosynostosis: an fMRI Study

Frustration and Emotional Regulation in Nonsyndromic Craniosynostosis: an fMRI Study

PURPOSE:Nonsyndromic craniosynostosis (NSC) may manifest with complex behavioral, attentional, and emotional sequelae. We characterized higher-level brain connectivity in adolescent NSC patients in response to emotional frustration. METHODS:Surgically corrected patients age >9 with NSC were age/g...

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Veröffentlicht in:Plastic and reconstructive surgery (1963) 2019-05
Hauptverfasser: Wu, Robin T, Yang, Jenny F, Zucconi, William, Lacadie, Cheryl, Swallow, Matthew, Sun, Alexander H, Eilbott, Jeffrey, Mayes, Linda C, Steinbacher, Derek M, Pelphrey, Kevin, Persing, John A
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Sprache:eng
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Zusammenfassung:PURPOSE:Nonsyndromic craniosynostosis (NSC) may manifest with complex behavioral, attentional, and emotional sequelae. We characterized higher-level brain connectivity in adolescent NSC patients in response to emotional frustration. METHODS:Surgically corrected patients age >9 with NSC were age/gender/handedness matched to controls. Patients participated in a GoNoGo task, structured as 'win/lose/recovery' paradigms; 'Win' allowed point increases, 'lose' led to net negative points, and 'recovery' allowed re-accumulation. BioImage Suite was used to analyze whole-brain intrinsic connectivity between tasks with cluster-corrected group-level T-maps. P
ISSN:0032-1052
1529-4242
DOI:10.1097/PRS.0000000000005850