Base-Promoted S N Ar Reactions of Fluoro- and Chloroarenes as a Route to N -Aryl Indoles and Carbazoles

Base-Promoted S N Ar Reactions of Fluoro- and Chloroarenes as a Route to N -Aryl Indoles and Carbazoles

KOH/DMSO-promoted C-N bond formation via nucleophilic aromatic substitution ( ) between chloroarenes or fluoroarenes with indoles and carbazole under transition metal-free conditions affording the corresponding -arylated indoles and carbazoles has been developed.

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Veröffentlicht in:Molecules (Basel, Switzerland) Switzerland), 2019-03, Vol.24 (6)
Hauptverfasser: Iqbal, Muhammad Asif, Mehmood, Hina, Lv, Jiaying, Hua, Ruimao
Format: Artikel
Sprache:eng
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Zusammenfassung:KOH/DMSO-promoted C-N bond formation via nucleophilic aromatic substitution ( ) between chloroarenes or fluoroarenes with indoles and carbazole under transition metal-free conditions affording the corresponding -arylated indoles and carbazoles has been developed.
ISSN:1420-3049
DOI:10.3390/molecules24061145